Meerarani Purushothaman
Overview
Explore the profile of Meerarani Purushothaman including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
202
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Recent Articles
1.
Krishnan P, Purushothaman K, Purushothaman M, Tarricone A, Chen S, Singla S, et al.
Cardiovasc Pathol
. 2019 Aug;
43:107139.
PMID: 31437716
Purpose: To investigate the cellular and extracellular changes induced by drug-coated balloons (DCB) in the treatment of superficial femoral artery (SFA) restenosis, and to compare histopathological features with those observed...
2.
Krishnan P, Moreno P, Turnbull I, Purushothaman M, Zafar U, Tarricone A, et al.
Vasc Med
. 2019 May;
24(5):383-394.
PMID: 31090495
Diabetes mellitus (DM) and chronic kidney disease (CKD) separately are known to facilitate the progression of medial arterial calcification (MAC) in patients with symptomatic peripheral artery disease (PAD), but their...
3.
Purushothaman K, Purushothaman M, Turnbull I, Adams D, Anyanwu A, Krishnan P, et al.
Cardiovasc Pathol
. 2017 Apr;
29:11-18.
PMID: 28453968
Background: Collagen cross-linking is mediated by lysyl oxidase (LOX) enzyme in the extracellular matrix (ECM) of mitral valve leaflets. Alterations in collagen content and LOX protein expression in the ECM...
4.
Krishnan P, Tarricone A, Purushothaman K, Purushothaman M, Vasquez M, Kovacic J, et al.
JACC Cardiovasc Interv
. 2017 Feb;
10(4):403-410.
PMID: 28231909
Objectives: This study sought to identify an algorithm for the use of distal embolic protection on the basis of angiographic lesion morphology and vascular anatomy for patients undergoing atherectomy for...
5.
Kini A, Vengrenyuk Y, Shameer K, Maehara A, Purushothaman M, Yoshimura T, et al.
J Am Coll Cardiol
. 2016 Dec;
69(6):628-640.
PMID: 27989886
Background: Despite extensive evidence demonstrating the beneficial effects of statins on clinical outcomes, the mechanisms underlying these effects remain elusive. Objectives: This study assessed changes in plaque morphology using intravascular...
6.
Krishnan P, Purushothaman K, Purushothaman M, Turnbull I, Tarricone A, Vasquez M, et al.
Atherosclerosis
. 2016 Jul;
251:226-233.
PMID: 27399649
Background And Aims: Neointimal cellular proliferation of fibroblasts and myofibroblasts is documented in coronary artery restenosis, however, their role in peripheral arterial disease (PAD) restenosis remains unclear. Our aim was...
7.
Krishnan P, Purushothaman K, Purushothaman M, Baber U, Tarricone A, Vasquez M, et al.
Am J Cardiol
. 2016 Feb;
117(7):1173-9.
PMID: 26857165
Smooth muscle cell proliferation and extracellular matrix formation are responsible for disease progression in de novo and restenotic atherosclerosis. Internal elastic lamella (IEL) layer maintains the structural integrity of intima,...
8.
Tarricone A, Ali Z, Rajamanickam A, Gujja K, Kapur V, Purushothaman K, et al.
J Endovasc Ther
. 2015 Jul;
22(5):712-5.
PMID: 26208657
Purpose: To investigate the impact on restenosis rates of deep injury to the adventitial layer during directional atherectomy. Methods: Between 2007 and 2010, 116 consecutive patients (mean age 69.6 years;...
9.
Purushothaman M, Krishnan P, Purushothaman K, Baber U, Tarricone A, Perez J, et al.
Arterioscler Thromb Vasc Biol
. 2012 Sep;
32(11):2769-75.
PMID: 22982461
Objective: Haptoglobin (Hp) protein is responsible for hemoglobin clearance after intra-plaque hemorrhage. Hp gene exists as Hp-1 and Hp-2 alleles and the phenotypes show important molecular heterogeneity. We tested the...
10.
Purushothaman K, Purushothaman M, Levy A, Lento P, Evrard S, Kovacic J, et al.
J Am Coll Cardiol
. 2012 Jul;
60(2):112-9.
PMID: 22766337
Objectives: The purpose of this study was to test the hypothesis that increased oxidative stress is associated with apoptosis in human plaques with the haptoglobin (Hp) 2-2 genotype. Background: Intraplaque...