Medha Rajappa
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Explore the profile of Medha Rajappa including associated specialties, affiliations and a list of published articles.
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98
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702
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Recent Articles
1.
Priyadarshini G, Dhinesh A, Parameswaran S, Sahoo J, Selvarajan S, Rajappa M
J Appl Genet
. 2025 Mar;
PMID: 40085338
The progressive degradation of the renal parenchyma and reduction of functional nephrons characterise chronic kidney disease (CKD). Disorders of bone mineral metabolism is one of the leading causes of morbidity...
2.
Goenka L, Dubashi B, Kayal S, Rajappa M, Manivannan P, Chakkalakkoombil S, et al.
Discov Oncol
. 2025 Feb;
16(1):203.
PMID: 39969689
Background: Autophagy activation contributes to chemotherapy resistance in several cancers, including ovarian cancer. Hydroxychloroquine (HCQ) is an autophagy inhibitor inhibiting the fusion of the autophagosome with the lysosome and has...
3.
Lakshminarayanan S, Muthu Kumaran P, Jayaram S, Mathaiyan J, Rajappa M
Monash Bioeth Rev
. 2025 Feb;
PMID: 39946007
Controlled Human Infection Studies (CHIS) involving the deliberate exposure of healthy individuals to infectious agents, are emerging as a valuable tool for medical research. This systematic survey explores the perceptions...
4.
Clinical relevance of Thiopurine methyl transferase genotype testing for azathioprine in dermatology
Ramassamy S, Chandrashekar L, Mathaiyan J, Rajappa M, Devanathan R, Selvarathinam S, et al.
Clin Exp Dermatol
. 2025 Feb;
PMID: 39920408
Background: Polymorphisms in thiopurine methyltransferase (TPMT) are a predominant cause of azathiopurine-induced leukopenia in the Western countries. The exact role of these polymorphisms in Indian population with dermatological disorders is...
5.
Lama M, Deepthi B, Krishnasamy S, Ganesh R, Srinivas B, Rajappa M, et al.
Pediatr Nephrol
. 2025 Feb;
PMID: 39891679
Background: Limited data exists on clinical predictors of kidney outcomes in children with lupus nephritis (LN). Methods: Children aged below 18 years with biopsy-proven LN followed from January 2010 to...
6.
Kumar A, Priyadarshini G, Parameswaran S, Ramesh A, Rajappa M
Cureus
. 2024 Sep;
16(8):e66494.
PMID: 39246913
Background Chronic kidney disease (CKD) leads to a progressive decline in renal function, primarily due to deteriorating kidney structures. Vascular calcification is a key effect of CKD. MicroRNAs (miRNAs) play...
7.
Priyadarshini G, Parameswaran S, Sahoo J, Selvarajan S, Ramesh A, Rajappa M
Int J Nephrol
. 2024 Sep;
2024:3850055.
PMID: 39246453
Background: Chronic kidney disease (CKD) is defined by gradual deterioration of renal parenchyma and decline of functioning nephrons. The risk of cardiovascular events is drastically increased in patients with CKD....
8.
Dhanyee A, Parida S, Thangaswamy C, Jha A, Rajappa M, Munuswamy H, et al.
Perfusion
. 2024 Jan;
40(1):164-173.
PMID: 38182129
Background: Modifiable and non-modifiable factors contribute to development and progression of acute kidney injury (AKI) during cardiac surgery. We hypothesized that, the difference between preoperative mean arterial pressure (MAP) and...
9.
Keshri N, Nandeesha H, Rajappa M, Menon V
J Neurosci Rural Pract
. 2023 Sep;
14(3):501-508.
PMID: 37692806
Objectives: Synaptic plasticity markers are known to alter in schizophrenia. The objective of the study was to investigate the genotype and allele frequency of neurotrophin-3 (NT-3) gene polymorphism (rs6489630, rs6332,...
10.
Rajasekharan A, Munisamy M, Menon V, Mohan Raj P, Priyadarshini G, Rajappa M
J Psychosom Res
. 2023 May;
170:111350.
PMID: 37207550
Background: Psoriasis is an immune-mediated, chronic inflammatory disease affecting mainly the skin. Chronic stress leads to the blunted hypothalamic-pituitary-adrenal axis (HPA) that might induce pro-inflammatory conditions. Hence, we assessed the...