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Maximilian Nagel

Explore the profile of Maximilian Nagel including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 151
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Recent Articles
1.
Zhang L, Nagel M, Olson W, Chesler A, OConnor D
Cell Rep . 2024 Aug; 43(9):114665. PMID: 39215998
The neural basis of tongue mechanosensation remains largely mysterious despite the tongue's high tactile acuity, sensitivity, and relevance to ethologically important functions. We studied terminal morphologies and tactile responses of...
2.
Ronan E, Gandhi A, Constantinescu B, Uchima Koecklin K, Guenther M, Nagel M, et al.
bioRxiv . 2024 May; PMID: 38765985
Pain is the anticipated output of the trigeminal sensory neurons that innervate the tooth's vital interior ; however, the contribution of intradental neurons to healthy tooth sensation has yet to...
3.
Nagel M, Niestroj M, Bansal R, Fleck D, Lampert A, Stopkova R, et al.
Elife . 2024 May; 12. PMID: 38747258
In most mammals, conspecific chemosensory communication relies on semiochemical release within complex bodily secretions and subsequent stimulus detection by the vomeronasal organ (VNO). Urine, a rich source of ethologically relevant...
4.
Ronan E, Nagel M, Emrick J
Front Pain Res (Lausanne) . 2024 Apr; 5:1376564. PMID: 38590718
Somatosensory innervation of the oral cavity enables the detection of a range of environmental stimuli including minute and noxious mechanical forces. The trigeminal sensory neurons underlie sensation originating from the...
5.
Zhang L, Nagel M, Olson W, Chesler A, OConnor D
bioRxiv . 2023 Aug; PMID: 37645855
The mammalian tongue is richly innervated with somatosensory, gustatory and motor fibers. These form the basis of many ethologically important functions such as eating, speaking and social grooming. Despite its...
6.
Lam R, von Buchholtz L, Falgairolle M, Osborne J, Frangos E, Servin-Vences M, et al.
Science . 2023 Aug; 381(6660):906-910. PMID: 37616369
Despite the potential importance of genital mechanosensation for sexual reproduction, little is known about how perineal touch influences mating. We explored how mechanosensation affords exquisite awareness of the genitals and...
7.
Nickolls A, OBrien G, Shnayder S, Zhang Y, Nagel M, Patapoutian A, et al.
Elife . 2022 Nov; 11. PMID: 36382883
Piezo1 is a stretch-gated ion channel required for mechanosensation in many organ systems. Recent findings point to a new role for Piezo1 in the gut, suggesting that it is a...
8.
Nagel M, Chesler A
Curr Opin Neurobiol . 2022 Jun; 75:102572. PMID: 35689908
PIEZO2 is a stretch-gated ion channel that is expressed at high levels in somatosensory neurons. Humans with rare mutations in the PIEZO2 gene have profound mechanosensory deficits that include a...
9.
Bansal R, Nagel M, Stopkova R, Sofer Y, Kimchi T, Stopka P, et al.
BMC Biol . 2021 Jun; 19(1):133. PMID: 34182994
Background: For many animals, chemosensory cues are vital for social and defensive interactions and are primarily detected and processed by the vomeronasal system (VNS). These cues are often inherently associated...
10.
Tsitoura C, Malinowski S, Mohrhardt J, Degen R, DiBenedictis B, Gao Y, et al.
J Neurosci . 2020 Apr; 40(21):4203-4218. PMID: 32312886
The accessory olfactory system controls social and sexual behavior. In the mouse accessory olfactory bulb, the first central stage of information processing along the accessory olfactory pathway, projection neurons (mitral...