Maxime Schrapp
Overview
Explore the profile of Maxime Schrapp including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
31
Followers
0
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Recent Articles
1.
Ferretti S, Hamon J, de Kanter R, Scheufler C, Andraos-Rey R, Barbe S, et al.
Nature
. 2024 Apr;
629(8011):443-449.
PMID: 38658754
The Werner syndrome RecQ helicase WRN was identified as a synthetic lethal target in cancer cells with microsatellite instability (MSI) by several genetic screens. Despite advances in treatment with immune...
2.
Heuser A, Abdul Rahman W, Bechter E, Blank J, Buhr S, Erdmann D, et al.
ChemMedChem
. 2024 Feb;
19(8):e202300613.
PMID: 38334957
The Werner Syndrome RecQ helicase (WRN) is a synthetic lethal target of interest for the treatment of cancers with microsatellite instability (MSI). Different hit finding approaches were initially tested. The...
3.
Ramirez J, Poirson J, Foltz C, Chebaro Y, Schrapp M, Meyer A, et al.
Angew Chem Int Ed Engl
. 2015 May;
54(27):7958-62.
PMID: 26014966
The E6 oncoproteins of high-risk mucosal (hrm) human papillomaviruses (HPVs) contain a pocket that captures LxxLL motifs and a C-terminal motif that recruits PDZ domains, with both functions being crucial...