Maxime M C Tortora
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Explore the profile of Maxime M C Tortora including associated specialties, affiliations and a list of published articles.
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10
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30
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Recent Articles
1.
Rahmaninejad H, Xiao Y, Tortora M, Fudenberg G
bioRxiv
. 2024 Oct;
PMID: 39416077
In mammalian interphase cells, genomes are folded by cohesin loop extrusion limited by directional CTCF barriers. This interplay leads to the enrichment of cohesin at barriers, isolation between neighboring topologically...
2.
Tortora M, Fudenberg G
bioRxiv
. 2024 Sep;
PMID: 39229088
Loop extrusion constitutes a universal mechanism of genome organization, whereby structural maintenance of chromosomes (SMC) protein complexes load onto the chromatin fiber and generate DNA loops of increasingly-larger sizes until...
3.
Grelet E, Tortora M
Nat Mater
. 2024 May;
23(9):1276-1282.
PMID: 38783105
Chirality is ubiquitous in nature across all length scales, with major implications spanning fields from biology, chemistry and physics to materials science. How chirality propagates from nanoscale building blocks to...
4.
Tortora M, Brennan L, Karpen G, Jost D
Proc Natl Acad Sci U S A
. 2023 Aug;
120(33):e2211855120.
PMID: 37549295
The spatial segregation of pericentromeric heterochromatin (PCH) into distinct, membrane-less nuclear compartments involves the binding of Heterochromatin Protein 1 (HP1) to H3K9me2/3-rich genomic regions. While HP1 exhibits liquid-liquid phase separation...
5.
Orsi G, Tortora M, Horard B, Baas D, Kleman J, Bucevicius J, et al.
Nat Commun
. 2023 Jul;
14(1):4187.
PMID: 37443316
Spermiogenesis is a radical process of differentiation whereby sperm cells acquire a compact and specialized morphology to cope with the constraints of sexual reproduction while preserving their main cargo, an...
6.
Abdulla A, Salari H, Tortora M, Vaillant C, Jost D
Curr Opin Genet Dev
. 2023 Mar;
79:102033.
PMID: 36893485
Recent experimental observations suggest a strong coupling between the 3D nuclear chromosome organization and epigenomics. However, the mechanistic and functional bases of such interplay remain elusive. In this review, we...
7.
Chhabra H, Mishra G, Cao Y, Presern D, Skoruppa E, Tortora M, et al.
J Chem Theory Comput
. 2020 Nov;
16(12):7748-7763.
PMID: 33164531
To study the elastic properties of rodlike DNA nanostructures, we perform long simulations of these structures using the oxDNA coarse-grained model. By analyzing the fluctuations in these trajectories, we obtain...
8.
Tortora M, Mishra G, Presern D, Doye J
Sci Adv
. 2020 Aug;
6(31):eaaw8331.
PMID: 32789165
Lyotropic cholesteric liquid crystal phases are ubiquitously observed in biological and synthetic polymer solutions, characterized by a complex interplay between thermal fluctuations and entropic and enthalpic forces. The elucidation of...
9.
Tortora M, Doye J
J Chem Phys
. 2017 Dec;
147(22):224504.
PMID: 29246043
We detail the application of bounding volume hierarchies to accelerate second-virial evaluations for arbitrary complex particles interacting through hard and soft finite-range potentials. This procedure, based on the construction of...
10.