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Maxime Francois

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Articles 28
Citations 272
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Recent Articles
1.
Francois M, Pascovici D, Wang Y, Vu T, Liu J, Beale D, et al.
Metabolites . 2024 Dec; 14(12). PMID: 39728495
As the burden of Alzheimer's disease (AD) escalates with an ageing population, the demand for early and accessible diagnostic methods becomes increasingly urgent. Saliva, with its non-invasive and cost-effective nature,...
2.
Vevelstad S, Grimstvedt A, Francois M, Knuutila H, Haugen G, Wiig M, et al.
Ind Eng Chem Res . 2023 Jan; 62(1):610-626. PMID: 36649443
Aqueous amine solvents are used to capture CO from various flue gas sources. In this work, the chemical stability of a blend of 3-amino-1-propanol (3A1P) and 1-(2-hydroxyethyl)pyrrolidine [1-(2HE)PRLD] was studied....
3.
McNicholas K, Francois M, Liu J, Doecke J, Hecker J, Faunt J, et al.
Front Aging Neurosci . 2022 Nov; 14:1019296. PMID: 36438010
Alzheimer's disease (AD) is an insidious disease. Its distinctive pathology forms over a considerable length of time without symptoms. There is a need to detect this disease, before even subtle...
4.
Francois M, Karpe A, Liu J, Beale D, Hor M, Hecker J, et al.
Metabolites . 2022 Oct; 12(10). PMID: 36295851
The metabolomic and proteomic basis of mild cognitive impairment (MCI) and Alzheimer's disease (AD) is poorly understood, and the relationships between systemic abnormalities in metabolism and AD/MCI pathogenesis is unclear....
5.
Crame E, Bowen J, Secombe K, Coller J, Francois M, Leifert W, et al.
Inflamm Intest Dis . 2022 Jan; 6(4):199-209. PMID: 35083285
Introduction: Toll-like receptor 4 (TLR4) is a highly conserved immunosurveillance protein of innate immunity, displaying well-established roles in homeostasis and intestinal inflammation. Current evidence shows complex relationships between TLR4 activation,...
6.
Tavakoli Shirazi P, Eadie L, Heatley S, Page E, Francois M, Hughes T, et al.
Cancer Gene Ther . 2022 Jan; 29(8-9):1140-1152. PMID: 35022522
TYK2-rearrangements have recently been identified in high-risk acute lymphoblastic leukemia (HR-ALL) cases and are associated with poor outcome. Current understanding of the leukemogenic potential and therapeutic targetability of activating TYK2...
7.
Francois M, Karpe A, Liu J, Beale D, Hor M, Hecker J, et al.
J Alzheimers Dis . 2021 Jun; 82(3):1301-1313. PMID: 34151801
Background: The metabolomic and proteomic basis of mild cognitive impairment (MCI) and Alzheimer's disease (AD) is poorly understood and the relationships between systemic abnormalities in metabolism and AD/AMCI pathogenesis are...
8.
Jankovic-Karasoulos T, McAninch D, Dixon C, Leemaqz S, Francois M, Leifert W, et al.
J Nutr Biochem . 2021 Jan; 90:108574. PMID: 33388345
Adequate Zinc (Zn) intake is required to prevent multiple teratogenic effects however deviations from adequate Zn intake, including high maternal Zn status, have been linked to increased incidence of pregnancy...
9.
Siddiqui M, Francois M, Rainey-Smith S, Martins R, Masters C, Ames D, et al.
Life (Basel) . 2020 Aug; 10(8). PMID: 32781776
In response to double-stranded breaks (DSBs) in chromosomal DNA, H2AX (a member of histone H2A family) becomes phosphorylated to form γH2AX. Although increased levels of γH2AX have been reported in...
10.
Habibi N, Jankovic-Karasoulos T, Leemaqz S, Francois M, Zhou S, Leifert W, et al.
Biol Trace Elem Res . 2020 Jul; 199(4):1332-1344. PMID: 32623623
Adequate maternal micronutrition is vital for placental formation, fetal growth, and development. Oxidative stress adversely affects placental development and function and an association between deficient placental development, oxidative stress, and...