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Maxim Pilyugin

Explore the profile of Maxim Pilyugin including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 260
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Recent Articles
1.
Pilyugin M, Ratajska M, Stukan M, Concin N, Zeillinger R, Irminger-Finger I
Genes (Basel) . 2021 Jul; 12(7). PMID: 34201956
Background: Ovarian cancer (OC) is the most lethal gynaecological cancer. It is often diagnosed at an advanced stage with poor chances for successful treatment. An accurate blood test for the...
2.
Pilyugin M, Descloux P, Andre P, Laszlo V, Dome B, Hegedus B, et al.
PLoS One . 2017 Aug; 12(8):e0182356. PMID: 28786985
Purpose: Currently the screening for lung cancer for risk groups is based on Computed Tomography (CT) or low dose CT (LDCT); however, the lung cancer death rate has not decreased...
3.
Pilyugin M, Andre P, Ratajska M, Kuzniacka A, Limon J, Tournier B, et al.
Oncotarget . 2016 Dec; 8(6):9339-9353. PMID: 28030839
Previous reports have shown that expression of BARD1δ, a deletion-bearing isoform of BARD1, correlates with tumor aggressiveness and progression. We show that expression of BARD1δ induces cell cycle arrest in...
4.
Irminger-Finger I, Ratajska M, Pilyugin M
Int J Biochem Cell Biol . 2016 Jan; 72:1-17. PMID: 26738429
For nearly two decades most research on BARD1 was closely linked to research on BRCA1, the breast cancer predisposition gene. The co-expression of BARD1 and BRCA1 genes in most tissues,...
5.
Ratajska M, Matusiak M, Kuzniacka A, Wasag B, Brozek I, Biernat W, et al.
Oncol Rep . 2015 Sep; 34(5):2609-17. PMID: 26329992
BARD1 is the main binding partner of BRCA1 and is required for its stability and tumor-suppressor functions. In breast cancer and other epithelial cell carcinomas, alternatively spliced isoforms of BARD1...
6.
Pilyugin M, Irminger-Finger I
Int J Biochem Cell Biol . 2014 Jul; 54:356-67. PMID: 25008968
Long non-coding RNAs (lncRNAs) are ubiquitously expressed RNA molecules of more than 200 nucleotides without substantial ORFs. LncRNAs could act as epigenetic regulators of gene expression affecting transcription, mRNA stability...
7.
Lepore I, DellAversana C, Pilyugin M, Conte M, Nebbioso A, De Bellis F, et al.
PLoS One . 2013 Dec; 8(12):e83018. PMID: 24349422
Over the past years BARD1 (BRCA1-associated RING domain 1) has been considered as both a BRCA1 (BReast Cancer susceptibility gene 1, early onset) interactor and tumor suppressor gene mutated in...
8.
Pilyugin M, Demmers J, Verrijzer C, Karch F, Moshkin Y
PLoS One . 2009 Dec; 4(12):e8328. PMID: 20016786
Histone chaperones are at the hub of a diverse interaction networks integrating a plethora of chromatin modifying activities. Histone H3/H4 chaperone ASF1 is a target for cell-cycle regulated Tousled-like kinases...
9.
Moshkin Y, Kan T, Goodfellow H, Bezstarosti K, Maeda R, Pilyugin M, et al.
Mol Cell . 2009 Sep; 35(6):782-93. PMID: 19782028
Histone chaperones are involved in a variety of chromatin transactions. By a proteomics survey, we identified the interaction networks of histone chaperones ASF1, CAF1, HIRA, and NAP1. Here, we analyzed...
10.
Pirrotta V, Poux S, Melfi R, Pilyugin M
Genetica . 2003 May; 117(2-3):191-7. PMID: 12723698
Polycomb complexes assemble at their target sites and silence neighboring genes when these are not actively transcribed. The action of these complexes and of Trithorax complexes bound to the Polycomb...