Max Cardenas-Fernandez
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Explore the profile of Max Cardenas-Fernandez including associated specialties, affiliations and a list of published articles.
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13
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50
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Recent Articles
1.
Subrizi F, Wang Y, Thair B, Mendez-Sanchez D, Roddan R, Cardenas-Fernandez M, et al.
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
133(34):18821-18827.
PMID: 38505091
The tetrahydroisoquinoline (THIQ) ring system is present in a large variety of structurally diverse natural products exhibiting a wide range of biological activities. Routes to mimic the biosynthetic pathways to...
2.
The Discovery of Imine Reductases and their Utilisation for the Synthesis of Tetrahydroisoquinolines
Cardenas-Fernandez M, Roddan R, Carter E, Hailes H, Ward J
ChemCatChem
. 2023 Apr;
15(3):e202201126.
PMID: 37081856
Imine reductases (IREDs) are NADPH-dependent enzymes with significant biocatalytic potential for the synthesis of primary, secondary, and tertiary chiral amines. Their applications include the reduction of cyclic imines and the...
3.
Flores-Fernandez C, Cardenas-Fernandez M, Lye G, Ward J
Enzyme Microb Technol
. 2022 Jun;
160:110071.
PMID: 35717862
Large amounts of pectin-rich biomass are generated worldwide yearly, which can be hydrolysed by pectinases to obtain bio-based chemical building blocks such as D-galacturonic acid (GalA). The aim of this...
4.
Cardenas-Fernandez M, Sinclair O, Ward J
Microb Biotechnol
. 2021 Oct;
15(1):305-317.
PMID: 34713952
Transaminases (TAs) are promising biocatalysts for chiral amine synthesis; however, only few thermophilic TAs have been described to date. In this work, a genome mining approach was taken to seek...
5.
Cardenas-Fernandez M, Subrizi F, Dobrijevic D, Hailes H, Ward J
Org Biomol Chem
. 2021 Jul;
19(29):6493-6500.
PMID: 34250527
Transketolase (TK) is a fundamentally important enzyme in industrial biocatalysis which carries out a stereospecific carbon-carbon bond formation, and is widely used in the synthesis of prochiral ketones. This study...
6.
Subrizi F, Wang Y, Thair B, Mendez-Sanchez D, Roddan R, Cardenas-Fernandez M, et al.
Angew Chem Int Ed Engl
. 2021 Jun;
60(34):18673-18679.
PMID: 34101966
The tetrahydroisoquinoline (THIQ) ring system is present in a large variety of structurally diverse natural products exhibiting a wide range of biological activities. Routes to mimic the biosynthetic pathways to...
7.
Flores-Fernandez C, Cardenas-Fernandez M, Dobrijevic D, Jurlewicz K, Zavaleta A, Ward J, et al.
Biotechnol Prog
. 2018 Oct;
35(1):e2728.
PMID: 30304581
Proteases are the most important group of industrial enzymes and they can be used in several fields including biorefineries for the valorization of industrial byproducts. In this study, we purified...
8.
Cardenas-Fernandez M, Hamley-Bennett C, Leak D, Lye G
Bioresour Technol
. 2018 Sep;
269:195-202.
PMID: 30172183
Sugar beet pulp (SBP) fractionated by steam explosion, released sugar beet pectin (SB-pectin) which was selectively hydrolysed using a novel α-l-arabinofuranosidase (AF), yielding monomeric l-arabinose (Ara) and a galacturonic acid...
9.
Cardenas-Fernandez M, Bawn M, Hamley-Bennett C, Bharat P, Subrizi F, Suhaili N, et al.
Faraday Discuss
. 2017 Jul;
202:415-431.
PMID: 28665423
Over 8 million tonnes of sugar beet are grown annually in the UK. Sugar beet pulp (SBP) is the main by-product of sugar beet processing which is currently dried and...
10.
Ward D, Hewitson P, Cardenas-Fernandez M, Hamley-Bennett C, Diaz-Rodriguez A, Douillet N, et al.
J Chromatogr A
. 2017 Apr;
1497:56-63.
PMID: 28366567
The isolation of component sugars from biomass represents an important step in the bioprocessing of sustainable feedstocks such as sugar beet pulp. Centrifugal partition chromatography (CPC) is used here, as...