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Max Borsche

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Articles 42
Citations 1003
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Recent Articles
1.
Andujar B, Pereira S, Busi S, Usnich T, Borsche M, Ertan S, et al.
Environ Int . 2024 Nov; 194:109151. PMID: 39571299
Pathogenic variants in the Leucine-rich repeat kinase 2 (LRRK2) gene are a primary monogenic cause of Parkinson's disease (PD). However, the likelihood of developing PD with inherited LRRK2 pathogenic variants...
2.
Westenberger A, Skrahina V, Usnich T, Beetz C, Vollstedt E, Laabs B, et al.
Brain . 2024 Aug; 147(8):2652-2667. PMID: 39087914
Estimates of the spectrum and frequency of pathogenic variants in Parkinson's disease (PD) in different populations are currently limited and biased. Furthermore, although therapeutic modification of several genetic targets has...
3.
Kading N, Waldeck F, Meier B, Boutin S, Borsche M, Balck A, et al.
Front Public Health . 2024 Jul; 12:1415778. PMID: 38979040
Trial Registration: DRKS.de, German Clinical Trials Register (DRKS), Identifier: DRKS00023418, Registered on 28 October 2020.
4.
Menon P, Sambin S, Criniere-Boizet B, Courtin T, Tesson C, Casse F, et al.
NPJ Parkinsons Dis . 2024 Mar; 10(1):72. PMID: 38553467
Bi-allelic pathogenic variants in PRKN are the most common cause of autosomal recessive Parkinson's disease (PD). 647 patients with PRKN-PD were included in this international study. The pathogenic variants present...
5.
Kluge A, Borsche M, Streubel-Gallasch L, Gul T, Schaake S, Balck A, et al.
Ann Neurol . 2024 Mar; 95(6):1173-1177. PMID: 38546204
Pathogenic variants in PRKN cause early-onset Parkinson's disease (PD), while the role of alpha-synuclein in PRKN-PD remains uncertain. One study performed a blood-based alpha-synuclein seed amplification assay (SAA) in PRKN-PD,...
6.
Milovanovic A, Dragasevic-Miskovic N, Thomsen M, Borsche M, Hinrichs F, Westenberger A, et al.
Mov Disord Clin Pract . 2024 Mar; 11(6):626-633. PMID: 38487929
Background: The newly discovered intronic repeat expansions in the genes encoding replication factor C subunit 1 (RFC1) and fibroblast growth factor 14 (FGF14) frequently cause late-onset cerebellar ataxia. Objectives: To...
7.
Diaw S, Borsche M, Streubel-Gallasch L, Dulovic-Mahlow M, Hermes J, Lenz I, et al.
NPJ Parkinsons Dis . 2023 Oct; 9(1):148. PMID: 37903765
Despite being a major component of Lewy bodies and Lewy neurites, pathogenic variants in the gene encoding alpha-Synuclein (α-Syn) are rare. To date, only four missense variants in the SNCA...
8.
Borsche M, Thomsen M, Szmulewicz D, Lubbers B, Hinrichs F, Lockhart P, et al.
J Neurol . 2023 Oct; 271(2):1023-1027. PMID: 37861706
No abstract available.
9.
Lange B, Jaeger V, Harries M, Rucker V, Streeck H, Blaschke S, et al.
Infection . 2023 Aug; 52(1):139-153. PMID: 37530919
Purpose: Despite the need to generate valid and reliable estimates of protection levels against SARS-CoV-2 infection and severe course of COVID-19 for the German population in summer 2022, there was...
10.
Borsche M, Berg D
Mov Disord . 2023 Jul; 38(8):1397-1398. PMID: 37489601
No abstract available.