Max A Thorwald
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Explore the profile of Max A Thorwald including associated specialties, affiliations and a list of published articles.
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21
Citations
106
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Recent Articles
11.
Dutta N, Gerke J, Odron S, Morris J, Hruby A, Castro Torres T, et al.
bioRxiv
. 2023 Dec;
PMID: 38077060
Small molecule inhibitors of the mitochondrial electron transport chain (ETC) hold significant promise to provide valuable insights to the field of mitochondrial research and aging biology. In this study, we...
12.
Zhang H, DAgostino C, Tulisiak C, Thorwald M, Bergkvist L, Lindquist A, et al.
Heliyon
. 2023 May;
9(4):e15622.
PMID: 37128335
Background: Epidemiological studies have variably linked air pollution to increased risk of Parkinson's disease (PD). However, there is little experimental evidence for this association. Alpha-synuclein (α-syn) propagation plays central roles...
13.
Johns A, Higuchi-Sanabria R, Thorwald M, Vilchez D
Curr Opin Neurobiol
. 2023 Jan;
78:102673.
PMID: 36621224
Mitochondrial fitness is critical to organismal health and its impairment is associated with aging and age-related diseases. As such, numerous quality control mechanisms exist to preserve mitochondrial stability, including the...
14.
Thorwald M, Silva J, Head E, Finch C
Alzheimers Dement
. 2022 Dec;
19(6):2605-2617.
PMID: 36536382
Positron emission tomography (PET) imaging studies of Alzheimer's disease (AD) patients show progressive increases of fibrillar Aβ-amyloid. Because current PET ligands underestimate nonfibrillar forms, we assayed soluble Aβ in AD...
15.
Garcia G, Bar-Ziv R, Averbukh M, Dasgupta N, Dutta N, Zhang H, et al.
Aging Cell
. 2022 Nov;
22(1):e13742.
PMID: 36404134
The actin cytoskeleton is a three-dimensional scaffold of proteins that is a regulatory, energyconsuming network with dynamic properties to shape the structure and function of the cell. Proper actin function...
16.
Rodriguez-Ortiz C, Thorwald M, Rodriguez R, Mejias-Ortega M, Kieu Z, Maitra N, et al.
Clin Exp Pharmacol Physiol
. 2022 Nov;
50(3):228-237.
PMID: 36398458
Metabolic syndrome (MetS) is a rapidly increasing health concern during midlife and is an emerging risk factor for the development of neurodegenerative diseases, such as Alzheimer's disease (AD). While angiotensin...
17.
Godoy-Lugo J, Thorwald M, Mendez D, Rodriguez R, Nakano D, Nishiyama A, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142809
Non-alcoholic fatty liver disease (NAFLD) affects up to 20% of the world's population. Overactivation of the angiotensin receptor type 1 (AT1) contributes to metabolic dysfunction and increased oxidant production, which...
18.
Shkirkova K, Lamorie-Foote K, Zhang N, Li A, Diaz A, Liu Q, et al.
J Alzheimers Dis
. 2022 Aug;
89(4):1263-1278.
PMID: 36031897
Background: Air pollution particulate matter (PM) is strongly associated with risks of accelerated cognitive decline, dementia and Alzheimer's disease. Ambient PM batches have variable neurotoxicity by collection site and season,...
19.
Thorwald M, Godoy-Lugo J, Rodriguez R, Stanhope K, Graham J, Havel P, et al.
Antioxidants (Basel)
. 2022 May;
11(5).
PMID: 35624791
The onset of type II diabetes increases the heart's susceptibility to oxidative damage because of the associated inflammation and diminished antioxidant response. Transcription factor NF-κB initiates inflammation while Nrf2 controls...
20.
Godoy-Lugo J, Thorwald M, Hui D, Nishiyama A, Nakano D, Sonanez-Organis J, et al.
Endocrine
. 2021 Jul;
75(1):92-107.
PMID: 34327606
Purpose: Angiotensin receptor blockers (ARBs) can ameliorate metabolic syndrome (MetS)-associated dyslipidemia, hepatic steatosis, and glucose intolerance, suggesting that angiotensin receptor (AT1) over-activation contributes to impaired lipid and glucose metabolism, which...