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Max A Alekseyev

Explore the profile of Max A Alekseyev including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 14374
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Recent Articles
1.
Barela Hudgell M, Momtaz F, Jafri A, Alekseyev M, Smith L
Genes (Basel) . 2024 Feb; 15(2). PMID: 38397211
The () gene family in the purple sea urchin, , encodes immune response proteins. The genes are clustered, surrounded by short tandem repeats, and some are present in genomic segmental...
2.
Zamyatin A, Avdeyev P, Liang J, Sharma A, Chen C, Lukyanchikova V, et al.
Gigascience . 2021 Mar; 10(3). PMID: 33718948
Background: Anopheles coluzzii and Anopheles arabiensis belong to the Anopheles gambiae complex and are among the major malaria vectors in sub-Saharan Africa. However, chromosome-level reference genome assemblies are still lacking...
3.
Avdeyev P, Alexeev N, Rong Y, Alekseyev M
Bioinformatics . 2020 Feb; 36(10):2993-3003. PMID: 32058559
Motivation: One of the key computational problems in comparative genomics is the reconstruction of genomes of ancestral species based on genomes of extant species. Since most dramatic changes in genomic...
4.
Waterhouse R, Aganezov S, Anselmetti Y, Lee J, Ruzzante L, Reijnders M, et al.
BMC Biol . 2020 Jan; 18(1):1. PMID: 31898513
Background: New sequencing technologies have lowered financial barriers to whole genome sequencing, but resulting assemblies are often fragmented and far from 'finished'. Updating multi-scaffold drafts to chromosome-level status can be...
5.
Avdeyev P, Jiang S, Alekseyev M
Evol Bioinform Online . 2019 Jun; 15:1176934318820534. PMID: 31217687
Reconstruction of the median genome consisting of linear chromosomes from three given genomes is known to be intractable. There exist efficient methods for solving a relaxed version of this problem,...
6.
Alexeev N, Alekseyev M
J Comput Biol . 2018 Aug; 25(11):1203-1219. PMID: 30133318
Construction of phylogenetic trees and networks for extant species from their characters represents one of the key problems in phylogenomics. While solution to this problem is not always uniquely defined...
7.
Avdeyev P, Jiang S, Alekseyev M
Front Genet . 2018 Jan; 8:212. PMID: 29312438
Genome rearrangements are large-scale evolutionary events that shuffle genomic architectures. The minimal number of such events between two genomes is often used in phylogenomic studies to measure the evolutionary distance...
8.
Aganezov S, Alekseyev M
BMC Bioinformatics . 2017 Dec; 18(Suppl 15):496. PMID: 29244014
Background: Despite the recent progress in genome sequencing and assembly, many of the currently available assembled genomes come in a draft form. Such draft genomes consist of a large number...
9.
Alexeev N, Alekseyev M
BMC Genomics . 2017 Jun; 18(Suppl 4):356. PMID: 28589865
Background: The ability to estimate the evolutionary distance between extant genomes plays a crucial role in many phylogenomic studies. Often such estimation is based on the parsimony assumption, implying that...
10.
Alexeev N, Avdeyev P, Alekseyev M
BMC Bioinformatics . 2017 Feb; 17(Suppl 14):418. PMID: 28185564
Background: Genome median and genome halving are combinatorial optimization problems that aim at reconstruction of ancestral genomes by minimizing the number of evolutionary events between them and genomes of the...