Mauro Cunha Xavier Pinto
Overview
Explore the profile of Mauro Cunha Xavier Pinto including associated specialties, affiliations and a list of published articles.
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26
Citations
261
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Recent Articles
1.
Carvalho G, Cavalcante D, Parreira R, Chiareli R, Ortiz Leoncini G, Gomez R, et al.
Neuroscience
. 2025 Jan;
568:116-129.
PMID: 39826672
L-proline is an amino acid with a unique cyclic structure, involvement in various physiological processes, such as protein synthesis, collagen production, and neurotransmission. This review explores the complex roles of...
2.
Furriel B, Furriel G, Cunha Xavier Pinto M, Lemos R
Front Syst Neurosci
. 2025 Jan;
18():1454336.
PMID: 39776892
Dysfunction in fear and stress responses is intrinsically linked to various neurological diseases, including anxiety disorders, depression, and Post-Traumatic Stress Disorder. Previous studies using in vivo models with Immediate-Extinction Deficit...
3.
Cavalcante D, Nunes A, da Silva E, de Carvalho G, Chiareli R, Oliveira-Lima O, et al.
Exp Neurol
. 2024 Oct;
383:115006.
PMID: 39424040
Glycine Transporter Type 1 (GlyT1) inhibition confers neuroprotection against different forms of cerebral damage. This effect occurs through the elevation of synaptic glycine concentrations, which enhances N-methyl-d-aspartate receptor (NMDAR) activation...
4.
de Carvalho G, Tambwe P, Nascimento L, Campos B, Chiareli R, Junior G, et al.
J Pharm Pharmacol
. 2024 Jul;
76(9):1199-1211.
PMID: 38982944
The Glycine Transporter Type 1 (GlyT1) significantly impacts central nervous system functions, influencing glycinergic and glutamatergic neurotransmission. Bitopertin, the first GlyT1 inhibitor in clinical trials, was developed for schizophrenia treatment...
5.
Rocha J, Krause R, Ribeiro C, Oliveira N, Ribeiro de Sousa L, Leandro Santos Jr J, et al.
ACS Appl Mater Interfaces
. 2024 Jul;
17(9):13094-13110.
PMID: 38973727
Cell-membrane hybrid nanoparticles (NPs) are designed to improve drug delivery, thermal therapy, and immunotherapy for several diseases. Here, we report the development of distinct biomimetic magnetic nanocarriers containing magnetic nanoparticles...
6.
Oliveira-Lima O, de Carvalho G, do Prado Assuncao L, Bailao A, Ulrich H, Marques B, et al.
Neurochem Res
. 2024 Jun;
49(9):2535-2555.
PMID: 38888830
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid-β, leading to N-methyl-D-aspartate (NMDA) receptor-dependent synaptic depression, spine elimination, and memory deficits. Glycine transporter type 1 (GlyT1)...
7.
Izidoro Ribeiro R, Carvalho G, Chiareli R, Vieira de Assis Lima I, Bellozi P, Oliveira-Lima O, et al.
Neurosci Lett
. 2024 Mar;
826:137715.
PMID: 38460902
The striatum, an essential component of the brain's motor and reward systems, plays a pivotal role in a wide array of cognitive processes. Its dysfunction is a hallmark of neurodegenerative...
8.
Carvalho G, Chiareli R, Pedrazzi J, Silva-Amaral D, Batista da Rocha A, Oliveira-Lima O, et al.
Neurochem Res
. 2023 Sep;
49(1):170-183.
PMID: 37684384
The glutamatergic hypothesis of schizophrenia suggests a correlation between NMDA receptor hypofunction and negative psychotic symptoms. It has been observed that the expression of the proline transporter (PROT) in the...
9.
Carvalho G, Chiareli R, Marques B, Parreira R, Gil E, de Carvalho F, et al.
Pharmacol Rep
. 2023 Jan;
75(2):276-292.
PMID: 36719635
Background: L-proline transporter (PROT/SLC6A7) is closely associated with glutamatergic neurotransmission, where L-proline modulates the NMDA receptor (NMDAR) function. NMDAR-mediated excitotoxicity is a primary cause of neuronal death following stroke, which...
10.
Maciel L, Ramalho R, Izidoro Ribeiro R, Cunha Xavier Pinto M, Pereira I, Vaz B
J Am Soc Mass Spectrom
. 2021 Aug;
32(10):2513-2518.
PMID: 34464122
This work describes the development of a system that combines a derivatization protocol based on the Katritzky reaction with paper spray ionization mass spectrometry (PSI-MS) for the analysis of amino...