Matthias Hammerschmidt
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Explore the profile of Matthias Hammerschmidt including associated specialties, affiliations and a list of published articles.
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123
Citations
4949
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Recent Articles
1.
Benard E, Hammerschmidt M
Differentiation
. 2025 Feb;
142:100838.
PMID: 39904689
Human wingless-type MMTV integration site family member 10A (WNT10A) is a secreted glycoprotein that is involved in signaling pathways essential to ectodermal organogenesis and tissue regeneration. WNT10A was first linked...
2.
Armistead J, Hopfl S, Goldhausen P, Muller-Hartmann A, Fahle E, Hatzold J, et al.
Cell Death Dis
. 2024 Oct;
15(10):746.
PMID: 39397024
Evasion of cell death is a hallmark of cancer, and consequently the induction of cell death is a common strategy in cancer treatment. However, the molecular mechanisms regulating different types...
3.
Borges A, Pinto-Teixeira F, Wibowo I, Pogoda H, Hammerschmidt M, Kawakami K, et al.
MicroPubl Biol
. 2024 Oct;
2024.
PMID: 39381636
Mutations in cause branchio-oto-renal syndrome (BOR) in humans and the equivalent condition in animal models. BOR is characterized by multi-organ malformations. To better understand the role of Eya1 in organogenesis...
4.
Zhong W, Neugebauer J, Pathak J, Li X, Pals G, Zillikens M, et al.
Cells
. 2024 Sep;
13(17.
PMID: 39273077
Plastin-3 (PLS3) encodes T-plastin, an actin-bundling protein mediating the formation of actin filaments by which numerous cellular processes are regulated. Loss-of-function genetic defects in PLS3 are reported to cause X-linked...
5.
Raote I, Rosendahl A, Hakkinen H, Vibe C, Kucukaylak I, Sawant M, et al.
Nat Commun
. 2024 Apr;
15(1):3302.
PMID: 38658535
Uncontrolled secretion of ECM proteins, such as collagen, can lead to excessive scarring and fibrosis and compromise tissue function. Despite the widespread occurrence of fibrotic diseases and scarring, effective therapies...
6.
Asif M, A Khayyat A, Alawbathani S, Abdullah U, Sanner A, Georgomanolis T, et al.
Genet Med
. 2024 Apr;
26(7):101143.
PMID: 38641995
Purpose: Neurodevelopmental disorders exhibit clinical and genetic heterogeneity, ergo manifest dysfunction in components of diverse cellular pathways; the precise pathomechanism for the majority remains elusive. Methods: We studied 5 affected...
7.
Benard E, Kucukaylak I, Hatzold J, Berendes K, Carney T, Beleggia F, et al.
Dev Dyn
. 2023 Oct;
253(6):566-592.
PMID: 37870737
Background: Mutations of human WNT10A are associated with odonto-ectodermal dysplasia syndromes. Here, we present analyses of wnt10a loss-of-function mutants in the zebrafish. Results: wnt10a mutant zebrafish embryos display impaired tooth...
8.
Hatzold J, Nett V, Brantsch S, Zhang J, Armistead J, Wessendorf H, et al.
PLoS Genet
. 2023 Aug;
19(8):e1010873.
PMID: 37566613
Aberrantly up-regulated activity of the type II transmembrane protease Matriptase-1 has been associated with the development and progression of a range of epithelial-derived carcinomas, and a variety of signaling pathways...
9.
Pogoda H, Riedl-Quinkertz I, Hammerschmidt M
Front Endocrinol (Lausanne)
. 2023 May;
14:1107339.
PMID: 37223044
The vertebral column, with the centra as its iteratively arranged building blocks, represents the anatomical key feature of the vertebrate phylum. In contrast to amniotes, where vertebrae are formed from...
10.
Zhang J, Richetti S, Ramezani T, Welcker D, Lutke S, Pogoda H, et al.
Matrix Biol
. 2022 Aug;
112:132-154.
PMID: 36007682
Hemicentins are large proteins of the extracellular matrix that belong to the fibulin family and play pivotal roles during development and homeostasis of a variety of invertebrate and vertebrate tissues....