Matthias Gehringer
Overview
Explore the profile of Matthias Gehringer including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
547
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0
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Recent Articles
11.
Gehringer M, Pape F, Mendez M, Barbie P, Unzue Lopez A, Lefranc J, et al.
ChemMedChem
. 2023 Jul;
18(19):e202300344.
PMID: 37485831
The Frontiers in Medicinal Chemistry (FiMC) is the largest international Medicinal Chemistry conference in the German speaking area and took place from April 3 to 5 2023 in Vienna (Austria)....
12.
Diamanti E, Mendez M, Ross T, Kuttruff C, Lefranc J, Klingler F, et al.
ChemMedChem
. 2022 Oct;
17(21):e202200419.
PMID: 36198574
The Frontiers in Medicinal Chemistry (FiMC) meeting, which represents the largest international medicinal chemistry conference in Germany, took place from March 14 to 16 2022 in a fully virtual format....
13.
Laufer S, Bajorath J, Gehringer M, Gray N, Frye S, Lindsley C
J Med Chem
. 2022 May;
65(10):6973-6974.
PMID: 35512193
No abstract available.
14.
Abdelmalek C, Hu Z, Kronenberger T, Kublbeck J, Kinnen F, Hesse S, et al.
J Med Chem
. 2022 Mar;
65(6):4616-4632.
PMID: 35286086
Anticancer drug conjugates may benefit from simultaneous action at two targets potentially overcoming the drawbacks of current cancer treatment, such as insufficient efficacy, high toxicity, and development of resistance. Compared...
15.
Serafim R, Da Silva Santiago A, Schwalm M, Hu Z, Dos Reis C, Takarada J, et al.
J Med Chem
. 2022 Feb;
65(4):3173-3192.
PMID: 35167750
Monopolar spindle kinase 1 (MPS1/TTK) is a key element of the mitotic checkpoint and clinically evaluated as a target in the treatment of aggressive tumors such as triple-negative breast cancer....
16.
Gerstenecker S, Haarer L, Schroder M, Kudolo M, Schwalm M, Wydra V, et al.
Cancers (Basel)
. 2021 Oct;
13(20).
PMID: 34680283
The ribosomal protein S6 kinase beta 2 (S6K2) is thought to play an important role in malignant cell proliferation, but is understudied compared to its closely related homolog S6 kinase...
17.
Serafim R, Elkins J, Zuercher W, Laufer S, Gehringer M
J Med Chem
. 2021 Sep;
65(2):1132-1170.
PMID: 34477374
Over 20 years after the approval of the first-in-class protein kinase inhibitor imatinib, the biological function of a significant fraction of the human kinome remains poorly understood while most research...
18.
Rocha C, Alves A, Bettanin B, Majolo F, Gehringer M, Laufer S, et al.
Inflammopharmacology
. 2021 May;
29(3):595-615.
PMID: 34046798
Objective: One-third of patients with severe rheumatoid arthritis (RA) do not achieve remission or low disease activity, or they have side effects from cDMARD and bDMARD. They will need a...
19.
Warryn L, Dangy J, Gersbach P, Gehringer M, Altmann K, Pluschke G
J Immunol
. 2021 May;
206(11):2753-2762.
PMID: 34031146
Mycolactone is a cytotoxin responsible for most of the chronic necrotizing pathology of disease (Buruli ulcer). The polyketide toxin consists of a 12-membered lactone ring with a lower -linked polyunsaturated...
20.
Saad H, Aziz S, Gehringer M, Kramer M, Straetener J, Berscheid A, et al.
Angew Chem Int Ed Engl
. 2021 May;
60(30):16472-16479.
PMID: 33991039
The increasing number of available genomes, in combination with advanced genome mining techniques, unveiled a plethora of biosynthetic gene clusters (BGCs) coding for ribosomally synthesized and post-translationally modified peptides (RiPPs)....