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Matthias Durken

Explore the profile of Matthias Durken including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 2578
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Recent Articles
11.
Karremann M, Kramer N, Hoffmann M, Wiese M, Beilken A, Corbacioglu S, et al.
Eur J Cancer . 2017 Jun; 81:1-8. PMID: 28586748
Background: Temozolomide (TMZ) is widely used in high-grade glioma (HGG). There is a major concern of treatment-induced secondary haematological malignancies (SHMs). Due to the poor overall survival of HGG patients,...
12.
Rettinger E, Merker M, Salzmann-Manrique E, Kreyenberg H, Krenn T, Durken M, et al.
Biol Blood Marrow Transplant . 2016 Oct; 23(1):87-95. PMID: 27742575
Monitoring of minimal residual disease (MRD) or chimerism may help guide pre-emptive immunotherapy (IT) with a view to preventing relapse in childhood acute lymphoblastic leukemia (ALL) after transplantation. Patients with...
13.
Bartelheim K, Nemes K, Seeringer A, Kerl K, Buechner J, Boos J, et al.
Cancer Med . 2016 May; 5(8):1765-75. PMID: 27228363
Atypical teratoid rhabdoid tumors (AT/RT) are characterized by mutations and subsequent inactivation of SMARCB1 (INI1, hSNF5), a predilection for very young children and an unfavorable outcome. The European Registry for...
14.
Vandenhaute E, Stump-Guthier C, Losada M, Tenenbaum T, Rudolph H, Ishikawa H, et al.
Cancer Cell Int . 2015 Oct; 15:102. PMID: 26500454
Background: The central nervous system (CNS) is protected by several barriers, including the blood-brain (BBB) and blood-cerebrospinal fluid (BCSFB) barriers. Understanding how cancer cells circumvent these protective barriers to invade...
15.
Karremann M, Sauerbier J, Meier C, Vetter C, Schneider H, Buchholz B, et al.
Leuk Lymphoma . 2014 Mar; 55(12):2874-8. PMID: 24576168
Abstract High-dose methotrexate (HD-MTX) is an important chemotherapy for various pediatric malignancies. However, in contrast to precise recommendations on supportive care following the start of HD-MTX infusion, studies on the...
16.
Sturm D, Witt H, Hovestadt V, Khuong-Quang D, Jones D, Konermann C, et al.
Cancer Cell . 2012 Oct; 22(4):425-37. PMID: 23079654
Glioblastoma (GBM) is a brain tumor that carries a dismal prognosis and displays considerable heterogeneity. We have recently identified recurrent H3F3A mutations affecting two critical amino acids (K27 and G34)...
17.
Gaiser T, Geissinger E, Schattenberg T, Scharf H, Durken M, Dinter D, et al.
Diagn Pathol . 2012 Apr; 7:38. PMID: 22497840
Primary involvement of skeletal muscle is a very rare event in ALK-1 positive anaplastic large cell lymphoma (ALCL). We describe a case of a 10-year old boy presenting with a...
18.
Schneider H, Geginat G, Hogardt M, Kramer A, Durken M, Schroten H, et al.
Pediatr Infect Dis J . 2012 Feb; 31(6):648-50. PMID: 22333699
We analyzed an outbreak of invasive infections with an exotoxin U positive Pseudomonas aeruginosa strain within a pediatric oncology care unit. Environmental sampling and molecular characterization of the Pseudomonas aeruginosa...
19.
Schwartzentruber J, Korshunov A, Liu X, Jones D, Pfaff E, Jacob K, et al.
Nature . 2012 Jan; 482(7384):226-31. PMID: 22286061
Glioblastoma multiforme (GBM) is a lethal brain tumour in adults and children. However, DNA copy number and gene expression signatures indicate differences between adult and paediatric cases. To explore the...
20.
Bader P, Soerensen J, Jarisch A, Ponstingl E, Krenn T, Faber J, et al.
Best Pract Res Clin Haematol . 2011 Sep; 24(3):331-7. PMID: 21925086
Allogeneic stem cell transplantation has become an important option in the curative treatment of many patients with malignant and non-malignant systemic diseases. Non-availability of HLA identical donors can limit access...