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Matthias Brauser

Explore the profile of Matthias Brauser including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
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Recent Articles
1.
Brauser M, Petzold K, Thiele C
Angew Chem Int Ed Engl . 2024 Dec; 64(10):e202421062. PMID: 39621941
Modern nuclear magnetic resonance (NMR) methods like carbon relaxation dispersion in the rotating frame (C-R) and proton chemical exchange saturation transfer (H-CEST) are key methods to investigate molecular recognition in...
2.
Herold D, Brauser M, Kind J, Thiele C
Chemistry . 2024 Feb; 30(23):e202304016. PMID: 38360972
The investigation of reaction mechanisms is a complex task that usually requires the use of several techniques. To obtain as much information as possible on the reaction and any intermediates...
3.
Nowag J, Brauser M, Steuernagel L, Wende R, R Schreiner P, Thiele C
J Am Chem Soc . 2023 Dec; 146(1):170-180. PMID: 38117177
The kinetic resolution of -cyclohexane-1,2-diol with a lipophilic oligopeptide catalyst shows extraordinary selectivities. To improve our understanding of the factors governing selectivity, we quantified the Gibbs free energies of interactions...
4.
Primozic J, Ilgen J, Maibach P, Brauser M, Kind J, Thiele C
J Am Chem Soc . 2023 Jul; 145(29):15912-15923. PMID: 37409501
The Pd-catalyzed allylic alkylation of 3,4-disubstituted, racemic cyclobutene electrophiles exhibits a highly unusual stereoselectivity that allows for controlling diastereo- and enantioselectivity only by the choice of ligand and independent of...
5.
Brauser M, Heymann T, Thiele C
Molecules . 2022 Oct; 27(19). PMID: 36234884
Until now, the intermediate responsible for the acyl transfer of a highly enantioselective tetrapeptide organocatalyst for the kinetic resolution of trans-cycloalkane-1,2-diols has never been directly observed. It was proposed computationally...
6.
Tietze D, Seth B, Brauser M, Tietze A, Buntkowsky G
Chemistry . 2018 Jul; 24(59):15879-15888. PMID: 30055023
A small, catalytically active metallopeptide (Nim SOD, m SOD=ACDLAC), which was derived from the nickel superoxide dismutase (NiSOD) active site was employed to study the mechanism of superoxide degradation, especially...