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Matthew Verbeek

Explore the profile of Matthew Verbeek including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 59
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Recent Articles
1.
Margolin E, Allen J, Verbeek M, Chapman R, Meyers A, van Diepen M, et al.
Biotechnol Bioeng . 2022 Jul; 119(10):2919-2937. PMID: 35781691
Heterologous glycoprotein production relies on host glycosylation-dependent folding. When the biosynthetic machinery differs from the usual expression host, there is scope to remodel the assembly pathway to enhance glycoprotein production....
2.
Margolin E, Verbeek M, de Moor W, Chapman R, Meyers A, Schafer G, et al.
Front Plant Sci . 2022 Jan; 12:798822. PMID: 35058959
Given the complex maturation requirements of viral glycoproteins and the challenge they often pose for expression in plants, the identification of host constraints precluding their efficient production is a priority...
3.
Margolin E, Allen J, Verbeek M, van Diepen M, Ximba P, Chapman R, et al.
Front Plant Sci . 2021 Aug; 12:709344. PMID: 34367227
There is an urgent need to establish large scale biopharmaceutical manufacturing capacity in Africa where the infrastructure for biologics production is severely limited. Molecular farming, whereby pharmaceuticals are produced in...
4.
Margolin E, Oh Y, Verbeek M, Naude J, Ponndorf D, Meshcheriakova Y, et al.
Plant Biotechnol J . 2020 Feb; 18(10):2109-2117. PMID: 32096288
Plant molecular farming (PMF) is rapidly gaining traction as a viable alternative to the currently accepted paradigm of producing biologics. While the platform is potentially cheaper and more scalable than...