Matthew R Young
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Explore the profile of Matthew R Young including associated specialties, affiliations and a list of published articles.
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51
Citations
1659
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Recent Articles
11.
Li W, Saud S, Young M, Colburn N, Hua B
Mol Cell Biochem
. 2015 Apr;
406(1-2):63-73.
PMID: 25912550
Cryptotanshinone (CPT) is a natural compound extracted from herbal medicine that has been previously shown to possess antitumor properties in various types of human cancer cells. In the present study,...
12.
Li W, Saud S, Young M, Chen G, Hua B
Oncotarget
. 2015 Mar;
6(10):7365-78.
PMID: 25812084
AMP-activated protein kinase (AMPK) is an important mediator in maintaining cellular energy homeostasis. AMPK is activated in response to a shortage of energy. Once activated, AMPK can promote ATP production...
13.
Perera T, Young M, Zhang Z, Murphy G, Colburn N, Lanza E, et al.
Mol Nutr Food Res
. 2015 Feb;
59(4):795-806.
PMID: 25641932
Scope: Aim of the study was to identify and monitor metabolite markers of dry bean consumption in parallel human and mouse studies that each had shown chemopreventive effects of dry...
14.
Ileva L, Bernardo M, Young M, Riffle L, Tatum J, Kalen J, et al.
Nat Protoc
. 2014 Oct;
9(11):2682-92.
PMID: 25340441
We have developed a reliable noninvasive method for monitoring colonic tumors and mucosal inflammation in a mouse model of colon cancer using magnetic resonance colonography (MRC). After a mild cleansing...
15.
Sagher E, Hernandez L, Heywood C, Pauly G, Young M, Schneider J, et al.
Cancer Cell Int
. 2014 Oct;
14:75.
PMID: 25324692
Background: The small molecule NSC676914A was previously identified as an NF-κB inhibitor in TPA-stimulated HEK293 cells (Mol Can Ther 8:571-581, 2009). We hypothesized that this effect would also be seen...
16.
Saud S, Li W, Morris N, Matter M, Colburn N, Kim Y, et al.
Carcinogenesis
. 2014 Oct;
35(12):2778-86.
PMID: 25280562
Sporadic and non-hereditary mutations account for the majority of colorectal cancers (CRC). After the loss of adenomatous polyposis coli (APC) function and activation of the β-catenin/LEF signaling pathway, activating mutations...
17.
Li W, Hua B, Saud S, Lin H, Hou W, Matter M, et al.
Mol Carcinog
. 2014 May;
54(10):1096-109.
PMID: 24838344
Colorectal cancer, a leading cause of cancer death, has been linked to inflammation and obesity. Berberine, an isoquinoline alkaloid, possesses anti-inflammatory, anti-diabetes and anti-tumor properties. In the azoxymethane initiated and...
18.
Wu L, Jiang H, Chawsheen H, Mishra M, Young M, Gerard M, et al.
Carcinogenesis
. 2014 Feb;
35(5):1177-84.
PMID: 24503444
Sulfiredoxin (Srx), the exclusive enzyme that reduces the hyperoxidized inactive form of peroxiredoxins (Prxs), has been found highly expressed in several types of human skin cancer. To determine whether Srx...
19.
Hwang S, Baker A, Young M, Colburn N
Carcinogenesis
. 2014 Jan;
35(7):1469-80.
PMID: 24413684
PDCD4 is a tumor suppressor induced by apoptotic stimuli that regulates both translation and transcription. Previously, we showed that overexpression of PDCD4 leads to decreased anchorage-independent growth in glioblastoma (GBM)-derived...
20.
Saud S, Young M, Jones-Hall Y, Ileva L, Evbuomwan M, Wise J, et al.
Cancer Res
. 2013 Jul;
73(17):5473-84.
PMID: 23824743
Analysis of the Polyp Prevention Trial showed an association between an isorhamnetin-rich diet and a reduced risk of advanced adenoma recurrence; however, the mechanism behind the chemoprotective effects of isorhamnetin...