Matthew R G Taylor
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Explore the profile of Matthew R G Taylor including associated specialties, affiliations and a list of published articles.
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129
Citations
4291
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Recent Articles
1.
Altman N, Gill E, Kahwash R, Meyer L, Wagner J, Karimpour-Fard A, et al.
Circ Heart Fail
. 2025 Mar;
:e012484.
PMID: 40052260
Background: Heart rate (HR) affects heart failure outcomes, via uncertain mechanisms that may include left ventricular remodeling. However, in human ventricular myocardium, HR change has not been associated with a...
2.
Ostrominski J, Claggett B, Jerosch-Herold M, Raja A, Day S, Russell M, et al.
JAMA Cardiol
. 2025 Mar;
PMID: 40042824
Importance: Valsartan has been shown to attenuate phenotypic progression among individuals with early-stage sarcomeric hypertrophic cardiomyopathy (HCM). Myocardial tissue characterization by cardiac magnetic resonance (CMR) imaging may enhance mechanistic insights,...
3.
Orchard P, Blackwell T, Kachuri L, Castaldi P, Cho M, Christenson S, et al.
medRxiv
. 2025 Mar;
PMID: 40034763
Most genetic variants associated with complex traits and diseases occur in non-coding genomic regions and are hypothesized to regulate gene expression. To understand the genetics underlying gene expression variability, we...
4.
Gigli M, Stolfo D, Barbati G, Graw S, Chen S, Merlo M, et al.
JAMA Cardiol
. 2025 Feb;
PMID: 39937464
Importance: Filamin C truncating variants (FLNCtv) are a rare cause of cardiomyopathy with heterogeneous phenotypic presentations. Despite a high incidence of life-threatening ventricular arrhythmias and sudden cardiac death (SCD), reliable...
5.
6.
Gigli M, Stolfo D, Merlo M, Sinagra G, Taylor M, Mestroni L
Nat Rev Cardiol
. 2024 Oct;
22(3):183-198.
PMID: 39394525
Dilated cardiomyopathy (DCM) is a complex disease with multiple causes and various pathogenic mechanisms. Despite improvements in the prognosis of patients with DCM in the past decade, this condition remains...
7.
Ireland C, Burstein D, Day S, Raja A, Russell M, Zahka K, et al.
Circ Heart Fail
. 2024 Aug;
17(8):e011663.
PMID: 39087355
Background: The health-related quality of life (HRQOL) and cardiopulmonary exercise testing (CPET) performance of individuals with subclinical and early stage hypertrophic cardiomyopathy (HCM) have not been systematically studied. Improved understanding...
8.
Zanetti M, Braidotti N, Khumar M, Montelongo E, Lombardi R, Sbaizero O, et al.
J Mech Behav Biomed Mater
. 2024 May;
155():106571.
PMID: 38744118
Cardiac fibrosis refers to the abnormal accumulation of extracellular matrix within the cardiac muscle, leading to increased stiffness and impaired heart function. From a rheological standpoint, knowledge about myocardial behavior...
9.
Castrichini M, De Luca A, De Angelis G, Neves R, Paldino A, Dal Ferro M, et al.
J Am Coll Cardiol
. 2024 May;
83(19):1841-1851.
PMID: 38719365
Background: Nondilated left ventricular cardiomyopathy (NDLVC) has been recently differentiated from dilated cardiomyopathy (DCM). A comprehensive characterization of these 2 entities using cardiac magnetic resonance (CMR) and genetic testing has...
10.
Defective Biomechanics and Pharmacological Rescue of Human Cardiomyocytes with Filamin C Truncations
Lazzarino M, Zanetti M, Chen S, Gao S, Pena B, Lam C, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38474188
Actin-binding filamin C (FLNC) is expressed in cardiomyocytes, where it localizes to Z-discs, sarcolemma, and intercalated discs. Although FLNC truncation variants () are an established cause of arrhythmias and heart...