Matthew Locke
Overview
Explore the profile of Matthew Locke including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
896
Followers
0
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Recent Articles
1.
Zaccagna F, McLean M, Grist J, Kaggie J, Mair R, Riemer F, et al.
Radiol Imaging Cancer
. 2022 Jul;
4(4):e210076.
PMID: 35838532
Purpose To evaluate glioblastoma (GBM) metabolism by using hyperpolarized carbon 13 (C) MRI to monitor the exchange of the hyperpolarized C label between injected [1-C]pyruvate and tumor lactate and bicarbonate....
2.
Locke M, Longstaff C, Rigsby P
J Thromb Haemost
. 2021 Mar;
19(3):852-858.
PMID: 33650255
The calibration of thrombin products relies on the World Health Organization (WHO) 2nd International Standard (IS) for Thrombin (01/580) which defines the international unit (IU) for thrombin potency. With stocks...
3.
Locke M, Longstaff C
Thromb Haemost
. 2020 Nov;
121(4):464-476.
PMID: 33131044
Histones released into circulation as neutrophil extracellular traps are causally implicated in the pathogenesis of arterial, venous, and microvascular thrombosis by promoting coagulation and enhancing clot stability. Histones induce structural...
4.
Woitek R, McLean M, Gill A, Grist J, Provenzano E, Patterson A, et al.
Radiol Imaging Cancer
. 2020 Aug;
2(4):e200017.
PMID: 32803167
Purpose: To compare hyperpolarized carbon 13 (C) MRI with dynamic contrast material-enhanced (DCE) MRI in the detection of early treatment response in breast cancer. Materials And Methods: In this institutional...
5.
Locke M, Francis R, Tsaousi E, Longstaff C
Sci Rep
. 2020 Jul;
10(1):11694.
PMID: 32678135
Neutrophils are pivotal players in immune defence which includes a process of release of histones and DNA as neutrophil extracellular traps (NETs). Histones, while toxic to invading pathogens, also kill...
6.
7.
Locke M, Rigsby P, Longstaff C
J Thromb Haemost
. 2020 Mar;
18(6):1501-1505.
PMID: 32112518
Streptokinase is used worldwide as a cost-effective treatment for acute myocardial infarction. Manufacturers use the World Health Organization (WHO) International Standard (IS) for Streptokinase to potency label their products, ensuring...
8.
Gallagher F, Woitek R, McLean M, Gill A, Manzano Garcia R, Provenzano E, et al.
Proc Natl Acad Sci U S A
. 2020 Jan;
117(4):2092-2098.
PMID: 31964840
Our purpose is to investigate the feasibility of imaging tumor metabolism in breast cancer patients using C magnetic resonance spectroscopic imaging (MRSI) of hyperpolarized C label exchange between injected [1-C]pyruvate...
9.
Chin J, Rees J, Locke M, Addy L
Br Dent J
. 2019 Jun;
226(11):867-870.
PMID: 31203340
Objectives To describe the approach taken by dental hygienists and therapists (DH/Ts) in Wales regarding dental implant maintenance. To gather their opinions about the current level of implant education.Materials and...
10.
Chin J, Addy L, Rees J, Locke M
Br Dent J
. 2019 May;
226(9):692-696.
PMID: 31076702
Objective The aim of this study was to assess the current status of implant teaching within dental hygiene and therapy schools in the UK and Ireland.Methods An online questionnaire relating...