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Matthew J Brooks

Explore the profile of Matthew J Brooks including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 925
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Recent Articles
1.
Campello L, Brooks M, Fadl B, Choi H, Pal S, Swaroop A
Aging Cell . 2025 Feb; :e70001. PMID: 39954235
Visual function deteriorates throughout the natural course of aging. Age-related structural and functional adaptations are observed in the retina, the light-sensitive neuronal tissue of the eye where visual perception begins....
2.
Tworak A, Kolesnikov A, Hong J, Choi E, Luu J, Palczewska G, et al.
Cell Rep . 2023 Aug; 42(8):112982. PMID: 37585292
In daylight, demand for visual chromophore (11-cis-retinal) exceeds supply by the classical visual cycle. This shortfall is compensated, in part, by the retinal G-protein-coupled receptor (RGR) photoisomerase, which is expressed...
3.
Brooks M
AMA J Ethics . 2022 Jul; 24(7):E634-637. PMID: 35838392
Stress and burnout afflict medical students and professionals at alarming rates, which has led institutions to invest in counseling services and other traditional wellness programming. However, the stigma of utilizing...
4.
Subramanian R, Brooks M
AMA J Ethics . 2022 Jul; 24(7):E584-589. PMID: 35838386
Background: Inspired by research indicating that exposure to humanities correlates with reduced burnout, the Nebraska Medical Orchestra was founded in 2018 as a collaboration between the University of Nebraska Medical...
5.
Liang X, Brooks M, Swaroop A
Hum Mol Genet . 2022 Jul; 31(22):3914-3933. PMID: 35776116
The basic motif-leucine zipper (bZIP) transcription factor neural retina leucine zipper (NRL) determines rod photoreceptor cell fate during retinal development, and its loss leads to cone-only retina in mice. NRL...
6.
Jiang K, Mondal A, Adlakha Y, Gumerson J, Aponte A, Gieser L, et al.
Hum Mol Genet . 2022 Jan; 31(13):2137-2154. PMID: 35075486
Retinal diseases exhibit extensive genetic heterogeneity and complex etiology with varying onset and severity. Mutations in over 200 genes can lead to photoreceptor dysfunction and/or cell death in retinal neurodegeneration....
7.
Han S, Okawa S, Wilkinson G, Ghazale H, Adnani L, Dixit R, et al.
Neuron . 2021 Aug; 109(18):2847-2863.e11. PMID: 34407390
Asymmetric neuronal expansion is thought to drive evolutionary transitions between lissencephalic and gyrencephalic cerebral cortices. We report that Neurog2 and Ascl1 proneural genes together sustain neurogenic continuity and lissencephaly in...
8.
DiStefano T, Chen H, Panebianco C, Kaya K, Brooks M, Gieser L, et al.
Stem Cell Reports . 2021 Jan; 16(1):224. PMID: 33440179
No abstract available.
9.
Vijayasarathy C, Zeng Y, Brooks M, Fariss R, Sieving P
Hum Gene Ther . 2020 Oct; 32(13-14):667-681. PMID: 33019822
To understand gene interaction networks in the X-linked retinoschisis (XLRS) mouse retina (), we analyzed the transcriptome by RNA sequencing before and after expression of exogenous retinoschisin () gene delivered...
10.
Phelan M, Kruczek K, Wilson J, Brooks M, Drinnan C, Regent F, et al.
Tissue Eng Part C Methods . 2020 Jul; 26(8):433-446. PMID: 32635833
Retinal pigment epithelium (RPE) differentiated from human induced pluripotent stem cells, called induced retinal pigment epithelium (iRPE), is being explored as a cell-based therapy for the treatment of retinal degenerative...