Matthew G Keefe
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Explore the profile of Matthew G Keefe including associated specialties, affiliations and a list of published articles.
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12
Citations
386
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Recent Articles
1.
Andrews J, Geng J, Voitiuk K, Elliott M, Shin D, Robbins A, et al.
Nat Neurosci
. 2024 Nov;
27(12):2487-2499.
PMID: 39548326
Seizures are made up of the coordinated activity of networks of neurons, suggesting that control of neurons in the pathologic circuits of epilepsy could allow for control of the disease....
2.
Barron J, Mroz N, Taloma S, Dahlgren M, Ortiz-Carpena J, Keefe M, et al.
Science
. 2024 Oct;
386(6721):eadi1025.
PMID: 39480923
The innate immune system shapes brain development and is implicated in neurodevelopmental diseases. It is critical to define the relevant immune cells and signals and their impact on brain circuits....
3.
Shin D, Kim C, Ross J, Hennick K, Wu S, Paranjape N, et al.
Cell Stem Cell
. 2024 Feb;
31(3):421-432.e8.
PMID: 38382530
Thalamic dysfunction has been implicated in multiple psychiatric disorders. We sought to study the mechanisms by which abnormalities emerge in the context of the 22q11.2 microdeletion, which confers significant genetic...
4.
Parks D, Voitiuk K, Geng J, Elliott M, Keefe M, Jung E, et al.
Internet Things (Amst)
. 2023 Jun;
20.
PMID: 37383277
The Internet of Things (IoT) provides a simple framework to control online devices easily. IoT is now a commonplace tool used by technology companies but is rarely used in biology...
5.
Allen D, Donohue K, Cadwell C, Shin D, Keefe M, Sohal V, et al.
Science
. 2022 May;
376(6600):1441-1446.
PMID: 35587512
Progenitors of the developing human neocortex reside in the ventricular and outer subventricular zones (VZ and OSVZ, respectively). However, whether cells derived from these niches have similar developmental fates is...
6.
Delgado R, Allen D, Keefe M, Leon W, Ziffra R, Crouch E, et al.
Nature
. 2021 Dec;
601(7893):397-403.
PMID: 34912114
The cerebral cortex is a cellularly complex structure comprising a rich diversity of neuronal and glial cell types. Cortical neurons can be broadly categorized into two classes-excitatory neurons that use...
7.
Voitiuk K, Geng J, Keefe M, Parks D, Sanso S, Hawthorne N, et al.
J Neural Eng
. 2021 Oct;
18(6).
PMID: 34666315
Neural activity represents a functional readout of neurons that is increasingly important to monitor in a wide range of experiments. Extracellular recordings have emerged as a powerful technique for measuring...
8.
Popova G, Soliman S, Kim C, Keefe M, Hennick K, Jain S, et al.
Cell Stem Cell
. 2021 Sep;
28(12):2153-2166.e6.
PMID: 34536354
Microglia are resident macrophages in the brain that emerge in early development and respond to the local environment by altering their molecular and phenotypic states. Fundamental questions about microglia diversity...
9.
Guo S, Yeh L, Folkesson J, Ivanov I, Krishnan A, Keefe M, et al.
Elife
. 2020 Jul;
9.
PMID: 32716843
We report quantitative label-free imaging with phase and polarization (QLIPP) for simultaneous measurement of density, anisotropy, and orientation of structures in unlabeled live cells and tissue slices. We combine QLIPP...
10.
Keefe M, Nowakowski T
Trends Neurosci
. 2020 Jan;
43(2):75-77.
PMID: 31954525
Haldipur et al. explored the developmental origins of the human cerebellum, which has gained growing appreciation for its involvement in human cognition. The authors discovered human-unique expansion and maintenance of...