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Matthew Eadens

Explore the profile of Matthew Eadens including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Haddad T, Qin R, Lupu R, Satele D, Eadens M, Goetz M, et al.
Cancer Chemother Pharmacol . 2017 May; 79(6):1221-1227. PMID: 28477227
Purpose: Cilengitide is a potent and selective inhibitor of the integrins αvβ3 and αvβ5. The primary objective of this phase I clinical trial was to establish the maximum tolerated dose...
2.
Puls L, Eadens M, Messersmith W
Oncologist . 2011 Apr; 16(5):566-78. PMID: 21521831
Summary: Src is believed to play an important role in cancer, and several agents targeting Src are in clinical development. Design: We reviewed Src structure and function and preclinical data...
3.
Spratlin J, Cohen R, Eadens M, Gore L, Camidge D, Diab S, et al.
J Clin Oncol . 2010 Jan; 28(5):780-7. PMID: 20048182
PURPOSE To evaluate the safety, maximum-tolerated dose (MTD), pharmacokinetics (PKs), pharmacodynamics, and preliminary anticancer activity of ramucirumab (IMC-1121B), a fully human immunoglobulin G(1) monoclonal antibody targeting the vascular endothelial growth...