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Matthew E Cove

Explore the profile of Matthew E Cove including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 369
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Recent Articles
1.
Cove M, Combes A, P Hilty M
Crit Care . 2025 Jan; 29(1):35. PMID: 39833959
No abstract available.
2.
Ang C, Chiew Y, Wang X, Ooi E, Cove M, Chen Y, et al.
Comput Methods Programs Biomed . 2024 Jul; 255:108323. PMID: 39029417
Background And Objective: Patient-ventilator asynchrony (PVA) is associated with poor clinical outcomes and remains under-monitored. Automated PVA detection would enable complete monitoring standard observational methods do not allow. While model-based...
3.
McGuigan P, Bowcock E, Barrett N, Blackwood B, Boyle A, Cadamy A, et al.
Crit Care Explor . 2024 Jan; 6(1):e1028. PMID: 38213419
Objectives: Lower tidal volume ventilation (targeting 3 mL/kg predicted body weight, PBW) facilitated by extracorporeal carbon dioxide removal (ECCOR) has been investigated as a potential therapy for acute hypoxemic respiratory...
4.
Hills T, Lorenzi E, Berry L, Shyamsundar M, Al-Beidh F, Annane D, et al.
N Engl J Med . 2023 Oct; 389(25):2341-2354. PMID: 37888913
Background: The efficacy of simvastatin in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. Methods: In an ongoing international, multifactorial, adaptive platform, randomized, controlled trial, we evaluated simvastatin...
5.
Adhikari N, Hashmi M, Vijayaraghavan B, Haniffa R, Beane A, Webb S, et al.
JAMA . 2023 Oct; 330(18):1745-1759. PMID: 37877585
Importance: The efficacy of vitamin C for hospitalized patients with COVID-19 is uncertain. Objective: To determine whether vitamin C improves outcomes for patients with COVID-19. Design, Setting, And Participants: Two...
6.
Chotirmall S, Abisheganaden J, Chew F, See K, Cove M, Goh A, et al.
Respirology . 2023 Aug; 28(10):966-968. PMID: 37648425
No abstract available.
7.
Ang C, Chiew Y, Wang X, Ooi E, Mat Nor M, Cove M, et al.
Comput Methods Programs Biomed . 2023 Aug; 240:107728. PMID: 37531693
Background And Objective: Healthcare datasets are plagued by issues of data scarcity and class imbalance. Clinically validated virtual patient (VP) models can provide accurate in-silico representations of real patients and...
8.
Ang C, Chiew Y, Wang X, Mat Nor M, Cove M, Chase J
Comput Biol Med . 2022 Nov; 151(Pt A):106275. PMID: 36375413
Background And Objective: Respiratory mechanics of mechanically ventilated patients evolve significantly with time, disease state and mechanical ventilation (MV) treatment. Existing deterministic data prediction methods fail to comprehensively describe the...
9.
Cove M, Pinsky M, Marini J
Crit Care . 2022 Oct; 26(1):309. PMID: 36217146
No abstract available.
10.
Ang C, Lee J, Chiew Y, Wang X, Tan C, Cove M, et al.
Comput Methods Programs Biomed . 2022 Oct; 226:107146. PMID: 36191352
Background And Objective: Model-based and personalised decision support systems are emerging to guide mechanical ventilation (MV) treatment for respiratory failure patients. However, model-based treatments require resource-intensive clinical trials prior to...