Matthew D Heath
Overview
Explore the profile of Matthew D Heath including associated specialties, affiliations and a list of published articles.
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35
Citations
337
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Recent Articles
1.
Layhadi J, Starchenka S, de Kam P, Palmer E, Patel N, Keane S, et al.
J Allergy Clin Immunol
. 2025 Jan;
155(1):153-165.
PMID: 39756833
Background: Peanut allergy (PA) is one of the most prevalent food allergies with a lack of favorable safety/efficacy treatment. A cucumber mosaic virus-like particle expressing peanut allergen component Ara h...
2.
Bachmann M, Krenger P, Mohsen M, Kramer M, Starchenka S, Whitehead P, et al.
Allergy
. 2024 Aug;
80(1):37-46.
PMID: 39189064
Type I hypersensitivity, also known as classical allergy, is mediated via allergen-specific IgE antibodies bound to type I FcR (FcεRI) on the surface of mast cells and basophils upon cross-linking...
3.
Krenger P, Josi R, Sobczak J, Velazquez T, Balke I, Skinner M, et al.
Allergy
. 2023 Oct;
79(1):184-199.
PMID: 37815010
Background: Virus-like particle (VLP) Peanut is a novel immunotherapeutic vaccine candidate for the treatment of peanut allergy. The active pharmaceutical ingredient represents cucumber mosaic VLPs (CuMV -VLPs) that are genetically...
4.
Sobczak J, Krenger P, Storni F, Mohsen M, Balke I, Resevica G, et al.
Allergy
. 2023 Mar;
78(7):1980-1996.
PMID: 36883475
Background: Allergy to peanut is one of the leading causes of anaphylactic reactions among food allergic patients. Immunization against peanut allergy with a safe and protective vaccine holds a promise...
5.
Grosch J, Lesur A, Kler S, Bernardin F, Dittmar G, Francescato E, et al.
Toxins (Basel)
. 2022 Apr;
14(4).
PMID: 35448893
Allergy to (European paper wasp) venom is of particular relevance in Southern Europe, potentially becoming a threat in other regions in the near future, and can be effectively cured by...
6.
Heldner A, Heath M, Schnautz B, Kotz S, Chaker A, Kramer M, et al.
Probiotics Antimicrob Proteins
. 2022 Feb;
15(4):868-879.
PMID: 35113319
Sensing of the intestinal microbiota by the host immune system is important to induce protective immune responses. Hence, modification of the gut microbiota might be able to prevent or treat...
7.
de Kam P, Kramer M, Shamji M, Oluwayi K, Heath M, Jensen-Jarolim E, et al.
World Allergy Organ J
. 2021 Oct;
14(9):100578.
PMID: 34659627
The concept of treatment of an allergy with the offending allergen was introduced more than a century ago. Allergen immunotherapy (AIT) is the only disease modifying treatment of allergic diseases...
8.
Feindor M, Heath M, Hewings S, Carreno Velazquez T, Blank S, Grosch J, et al.
Toxins (Basel)
. 2021 Sep;
13(9).
PMID: 34564620
In this review, we outline and reflect on the important differences between allergen-specific immunotherapy for inhalant allergies (i.e., aeroallergens) and venom-specific immunotherapy (VIT), with a special focus on Venomil Bee...
9.
Heldner A, Alessandrini F, Russkamp D, Heine S, Schnautz B, Chaker A, et al.
Allergy
. 2021 Jul;
77(3):907-919.
PMID: 34287971
Background: Native allergen extracts or chemically modified allergoids are routinely used to induce allergen tolerance in allergen-specific immunotherapy (AIT), although mechanistic side-by-side studies are rare. It is paramount to balance...
10.
Heath M, Mohsen M, de Kam P, Carreno Velazquez T, Hewings S, Kramer M, et al.
Front Immunol
. 2020 Dec;
11:594911.
PMID: 33324411
The concept of adjuvants or adjuvant systems, used in vaccines, exploit evolutionary relationships associated with how the immune system may initially respond to a foreign antigen or pathogen, thus mimicking...