Matthew D Daugherty
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Explore the profile of Matthew D Daugherty including associated specialties, affiliations and a list of published articles.
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45
Citations
1799
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Recent Articles
11.
Kalluraya C, Weitzel A, Tsu B, Daugherty M
Proc Natl Acad Sci U S A
. 2023 Aug;
120(34):e2310867120.
PMID: 37579166
No abstract available.
12.
Castro L, Daugherty M
Curr Opin Immunol
. 2023 Jun;
83:102354.
PMID: 37311351
Host innate immune sensors are vital for the initial detection of pathogen infection. Such sensors thus need to constantly adapt in escalating evolutionary arms races with pathogens. Recently, two inflammasome-forming...
13.
Tsu B, Agarwal R, Gokhale N, Kulsuptrakul J, Ryan A, Fay E, et al.
PLoS Biol
. 2023 Jun;
21(6):e3002144.
PMID: 37289745
Hosts have evolved diverse strategies to respond to microbial infections, including the detection of pathogen-encoded proteases by inflammasome-forming sensors such as NLRP1 and CARD8. Here, we find that the 3CL...
14.
Delgado-Rodriguez S, Ryan A, Daugherty M
Pathogens
. 2023 May;
12(5).
PMID: 37242344
Protein post-translational modifications (PTMs) are an important battleground in the evolutionary arms races that are waged between the host innate immune system and viruses. One such PTM, ADP-ribosylation, has recently...
15.
Kalluraya C, Weitzel A, Tsu B, Daugherty M
Proc Natl Acad Sci U S A
. 2023 Apr;
120(16):e2214815120.
PMID: 37036996
The vertebrate eye was described by Charles Darwin as one of the greatest potential challenges to a theory of natural selection by stepwise evolutionary processes. While numerous evolutionary transitions that...
16.
Schindewolf C, Lokugamage K, Vu M, Johnson B, Scharton D, Plante J, et al.
J Virol
. 2023 Feb;
97(2):e0153222.
PMID: 36722972
Understanding the molecular basis of innate immune evasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important consideration for designing the next wave of therapeutics. Here, we investigate...
17.
Wang B, Pandey T, Long Y, Delgado-Rodriguez S, Daugherty M, Ma D
Curr Biol
. 2022 Oct;
32(22):4941-4948.e3.
PMID: 36223775
Amygdalin is a cyanogenic glycoside enriched in the tissues of many edible plants, including seeds of stone fruits such as cherry (Prunus avium), peach (Prunus persica), and apple (Malus domestica)....
18.
Stevens D, Beierschmitt C, Mahesula S, Corley M, Salogiannis J, Tsu B, et al.
Elife
. 2022 Oct;
11.
PMID: 36222652
Viruses interact with the intracellular transport machinery to promote viral replication. Such host-virus interactions can drive host gene adaptation, leaving signatures of pathogen-driven evolution in host genomes. Here, we leverage...
19.
Schindewolf C, Lokugamage K, Vu M, Johnson B, Scharton D, Plante J, et al.
bioRxiv
. 2022 Oct;
PMID: 36203546
Importance: Similar to other coronaviruses, disruption of SARS-CoV-2 NSP16 function attenuates viral replication in a type I interferon-dependent manner. , our results show reduced disease and viral replication at late...
20.
Tsu B, Agarwal R, Gokhale N, Kulsuptrakul J, Ryan A, Castro L, et al.
bioRxiv
. 2022 Sep;
PMID: 36172130
Hosts have evolved diverse strategies to respond to microbial infections, including the detection of pathogen-encoded proteases by inflammasome-forming sensors such as NLRP1 and CARD8. Here, we find that the 3CL...