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Matthew Cairns

Explore the profile of Matthew Cairns including associated specialties, affiliations and a list of published articles. Areas
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Articles 54
Citations 1481
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Recent Articles
1.
Dicko A, Ouedraogo J, Zongo I, Sagara I, Cairns M, Yerbanga R, et al.
Lancet Infect Dis . 2023 Aug; 24(1):75-86. PMID: 37625434
Background: Seasonal vaccination with the RTS,S/AS01 vaccine combined with seasonal malaria chemoprevention (SMC) prevented malaria in young children more effectively than either intervention given alone over a 3 year period....
2.
Okell L, Kwambai T, Dhabangi A, Khairallah C, Nkosi-Gondwe T, Winskill P, et al.
Nat Commun . 2023 Jan; 14(1):402. PMID: 36697413
Children recovering from severe malarial anaemia (SMA) remain at high risk of readmission and death after discharge from hospital. However, a recent trial found that post-discharge malaria chemoprevention (PDMC) with...
3.
Cairns M, Barry A, Zongo I, Sagara I, Yerbanga S, Diarra M, et al.
BMC Med . 2022 Oct; 20(1):352. PMID: 36203149
Background: A recent trial of 5920 children in Burkina Faso and Mali showed that the combination of seasonal vaccination with the RTS,S/AS01 malaria vaccine (primary series and two seasonal boosters)...
4.
Datoo M, Natama H, Some A, Bellamy D, Traore O, Rouamba T, et al.
Lancet Infect Dis . 2022 Sep; 22(12):1728-1736. PMID: 36087586
Background: Malaria is a leading cause of morbidity and mortality worldwide. We previously reported the efficacy of the R21/Matrix-M malaria vaccine, which reached the WHO-specified goal of 75% or greater...
5.
Akinnawo A, Seyram K, Boamah Kaali E, Harrison S, Dosoo D, Cairns M, et al.
Malar J . 2022 Aug; 21(1):240. PMID: 35987638
Background: Malaria infection during pregnancy can cause significant morbidity and mortality to a pregnant woman, her fetus and newborn. In areas of high endemic transmission, gravidity is an important risk...
6.
Grant J, Sagara I, Zongo I, Cairns M, Yerbanga R, Diarra M, et al.
Malar J . 2022 Feb; 21(1):59. PMID: 35193608
Background: A recent trial in Burkina Faso and Mali showed that combining seasonal RTS,S/AS01 malaria vaccination with seasonal malaria chemoprevention (SMC) substantially reduced the incidence of uncomplicated and severe malaria...
7.
Sagara I, Zongo I, Cairns M, Yerbanga R, Mahamar A, Nikiema F, et al.
Clin Infect Dis . 2021 Dec; 75(4):613-622. PMID: 34894221
Background: A trial in African children showed that combining seasonal vaccination with the RTS,S/AS01E vaccine with seasonal malaria chemoprevention reduced the incidence of uncomplicated and severe malaria compared with either...
8.
Gutman J, Khairallah C, Stepniewska K, Tagbor H, Madanitsa M, Cairns M, et al.
EClinicalMedicine . 2021 Nov; 41:101160. PMID: 34746720
Background: In sub-Saharan Africa, the efficacy of intermittent preventive therapy in pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) for malaria in pregnancy is threatened by parasite resistance. We conducted an individual-participant data (IPD)...
9.
Cairns M, Ceesay S, Sagara I, Zongo I, Kessely H, Gamougam K, et al.
PLoS Med . 2021 Sep; 18(9):e1003727. PMID: 34495978
Background: Seasonal malaria chemoprevention (SMC) has shown high protective efficacy against clinical malaria and severe malaria in a series of clinical trials. We evaluated the effectiveness of SMC treatments against...
10.
Greenwood B, Cairns M, Chaponda M, Chico R, Dicko A, Ouedraogo J, et al.
Malar J . 2021 Sep; 20(1):361. PMID: 34488784
Malaria control has stalled in a number of African countries and novel approaches to malaria control are needed for these areas. The encouraging results of a recent trial conducted in...