Matthew Bunce
Overview
Explore the profile of Matthew Bunce including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
35
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0
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Recent Articles
1.
Bunce M, Huang Devine Z, Chintala M
Res Pract Thromb Haemost
. 2024 Dec;
8(8):102600.
PMID: 39687926
Background: The development of anticoagulants that provide antithrombotic efficacy without a concomitant bleeding risk remains an unmet clinical need in thrombosis. Although direct oral anticoagulants (DOACs) have a reduced incidence...
2.
Guo X, Kolpakov M, Hooshdaran B, Schappell W, Wang T, Eguchi S, et al.
JACC Basic Transl Sci
. 2020 Feb;
5(1):69-83.
PMID: 32043021
Activated factor X is a key component of the coagulation cascade, but whether it directly regulates pathological cardiac remodeling is unclear. In mice subjected to pressure overload stress, cardiac factor...
3.
Huang Devine Z, Du F, Li Q, Bunce M, Lacy E, Chintala M
J Pharmacol Exp Ther
. 2019 Aug;
371(2):375-384.
PMID: 31451508
JNJ-64179375 (JNJ-9375) is a recombinant human IgG4 monoclonal antibody engineered to mimic an IgA antibody that was identified in a patient who exhibited markedly prolonged clotting times but without spontaneous...
4.
Labrijn A, Meesters J, Bunce M, Armstrong A, Somani S, Nesspor T, et al.
Sci Rep
. 2017 Jun;
7(1):2476.
PMID: 28559564
Therapeutic concepts exploiting tumor-specific antibodies are often established in pre-clinical xenograft models using immuno-deficient mice. More complex therapeutic paradigms, however, warrant the use of immuno-competent mice, that more accurately capture...