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Matt Britz

Explore the profile of Matt Britz including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Yang Y, Louie R, Puc J, Vedvyas Y, Alcaina Y, Min I, et al.
Cancers (Basel) . 2023 Dec; 15(23). PMID: 38067255
Epithelial cell adhesion molecule (EpCAM) is a tumor-associated antigen that is frequently overexpressed in various carcinomas. We have developed chimeric antigen receptor (CAR) T cells specifically targeting EpCAM for the...
2.
Yang Y, Yang H, Alcaina Y, Puc J, Birt A, Vedvyas Y, et al.
Nat Commun . 2023 Apr; 14(1):2068. PMID: 37045815
The limited number of targetable tumor-specific antigens and the immunosuppressive nature of the microenvironment within solid malignancies represent major barriers to the success of chimeric antigen receptor (CAR)-T cell therapies....