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Matlock A Jeffries

Explore the profile of Matlock A Jeffries including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 720
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Recent Articles
1.
Dyson G, Barrett M, Schlupp L, Prinz E, Hannebut N, Szymczak A, et al.
ACR Open Rheumatol . 2025 Jan; 7(1):e11794. PMID: 39853943
Objectives: Dietary interventions are a potentially powerful treatment option for knee osteoarthritis (OA). The objective of this study was to evaluate a well-formulated ketogenic diet (KD) in the context of...
2.
Griffin T, Lopes E, Cortassa D, Batushansky A, Jeffries M, Makosa D, et al.
Biol Sex Differ . 2024 Dec; 15(1):103. PMID: 39639386
Background: Women have a higher risk of developing osteoarthritis (OA) than men, including with obesity. To better understand this disparity, we investigated sex differences in metabolic and inflammatory factors associated...
3.
Prinz E, Schlupp L, Dyson G, Barrett M, Szymczak A, Velasco C, et al.
Ann Rheum Dis . 2023 Nov; 83(3):382-393. PMID: 37979958
Objectives: The Murphy Roths Large (MRL)/MpJ 'superhealer' mouse strain is protected from post-traumatic osteoarthritis (OA), although no studies have evaluated the microbiome in the context of this protection. This study...
4.
Izda V, Schlupp L, Prinz E, Dyson G, Barrett M, Dunn C, et al.
Geroscience . 2023 Nov; 46(2):2317-2341. PMID: 37946009
Cartilage microbial DNA patterns have been recently characterized in osteoarthritis (OA). The objectives of this study were to evaluate the gut origins of cartilage microbial DNA, to characterize cartilage microbial...
5.
Schlupp L, Prinz E, Dyson G, Barrett M, Izda V, Dunn C, et al.
Arthritis Rheumatol . 2023 Aug; 76(2):231-237. PMID: 37651283
Objective: Females have reduced osteoarthritis (OA) in surgical models. The objective of the current study was to evaluate a sex-linked gut microbiome in the pathogenesis of OA. Methods: We induced...
6.
Dunn C, Sturdy C, Velasco C, Schlupp L, Prinz E, Izda V, et al.
Arthritis Rheumatol . 2022 Nov; 75(1):28-40. PMID: 36411273
Objective: The lack of accurate biomarkers to predict knee osteoarthritis (OA) progression is a key unmet need in OA clinical research. The objective of this study was to develop baseline...
7.
Izda V, Dunn C, Prinz E, Schlupp L, Nguyen E, Sturdy C, et al.
ACR Open Rheumatol . 2022 Oct; 4(12):1004-1012. PMID: 36253145
Objective: Cartilage epigenetic changes are strongly associated with human osteoarthritis (OA). However, the influence of individual environmental OA risk factors on these epigenetic patterns has not been determined; herein we...
8.
Dunn C, Jeffries M
Curr Rheumatol Rep . 2022 Apr; 24(5):139-148. PMID: 35389162
Purpose Of The Review: The microbiome has recently emerged as a powerful contributor to health and illness in chronic, systemic disorders. Furthermore, new microbiome niches beyond traditional gut locations are...
9.
Izda V, Martin J, Sturdy C, Jeffries M
Osteoarthr Cartil Open . 2022 Apr; 3(4). PMID: 35360044
Introduction: Osteoarthritis (OA) is a chronic musculoskeletal disease characterized by progressive loss of joint function. Historically, it has been characterized as a disease caused by mechanical trauma, so-called 'wear and...
10.
Velasco C, Dunn C, Sturdy C, Izda V, Martin J, Rivas A, et al.
PLoS One . 2021 Jul; 16(7):e0248322. PMID: 34283837
Objective: Adult elastic cartilage has limited repair capacity. MRL/MpJ (MRL) mice, by contrast, are capable of spontaneously healing ear punctures. This study was undertaken to characterize microbiome differences between healer...