Matic Legisa
Overview
Explore the profile of Matic Legisa including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
223
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Recent Articles
1.
Andrejc D, Legisa M
Biochim Biophys Acta Proteins Proteom
. 2018 Mar;
1866(5-6):602-607.
PMID: 29563071
Purpose: Cancer cells consume more glucose than normal human cells and convert most glucose into lactate. It has been proposed that deregulated glycolysis is triggered by the posttranslational modification of...
2.
Andrejc D, Mozir A, Legisa M
BMC Biotechnol
. 2017 May;
17(1):41.
PMID: 28482870
Background: At first glance, there appears to be a high degree of similarity between the metabolism of yeast (the Crabtree effect) and human cancer cells (the Warburg effect). At the...
3.
Bencina M, Legisa M
Pflugers Arch
. 2017 Feb;
439(Suppl 1):r076-r078.
PMID: 28176079
The transcriptional regulation of the pkaC gene, encoding the catalytic subunit of cAMP-dependent protein kinase from Aspergillus niger, was analysed under different environmental conditions. Quantitative determination of pkaC transcript showed...
4.
Papagianni M, Legisa M
J Biotechnol
. 2014 Apr;
181:20-6.
PMID: 24742994
Based on established knowledge of the simultaneous use of the phosphoketolase pathway (PKP) and the Embden-Meyerhof pathway (EMP) - as a secondary pathway with a smaller flux - by mannitol...
5.
Smerc A, Sodja E, Legisa M
PLoS One
. 2011 May;
6(5):e19645.
PMID: 21573193
Background: Human cancers consume larger amounts of glucose compared to normal tissues with most being converted and excreted as lactate despite abundant oxygen availability (Warburg effect). The underlying higher rate...
6.
Usenik A, Legisa M
PLoS One
. 2010 Dec;
5(11):e15447.
PMID: 21124851
As an important part of metabolism, metabolic flux through the glycolytic pathway is tightly regulated. The most complex control is exerted on 6-phosphofructo-1-kinase (PFK1) level; this control overrules the regulatory...
7.
Tevz G, Bencina M, Legisa M
Appl Microbiol Biotechnol
. 2010 May;
87(5):1657-64.
PMID: 20461508
Aspergillus terreus is successfully used for industrial production of itaconic acid. The acid is formed from cis-aconitate, an intermediate of the tricarboxylic (TCA) cycle, by catalytic action of cis-aconitate decarboxylase....
8.
Capuder M, Solar T, Bencina M, Legisa M
J Biotechnol
. 2009 Apr;
144(1):51-7.
PMID: 19379783
In Aspergillus niger cells spontaneous posttranslational modification of 6-phosphofructo-1-kinase (PFK1) occurs. In a two step process the native enzyme (85kDa) is first cleaved to an inactive fragment (49kDa) that regains...
9.
Solar T, Tursic J, Legisa M
Appl Microbiol Biotechnol
. 2008 Jan;
78(4):613-9.
PMID: 18214472
Glucosamine-6-phosphate (GlcN6P) deaminase seems to be the main enzyme in Aspergillus niger cells responsible for rapid glucosamine accumulation during the early stages of growth in a high-citric-acid-yielding medium. By determining...
10.
Berovic M, Legisa M
Biotechnol Annu Rev
. 2007 Sep;
13:303-43.
PMID: 17875481
Citric acid is a commodity chemical produced and consumed throughout The World. It is used mainly in the food and beverage industry, primarily as an acidulant. Although it is one...