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Mateusz S Wietecha

Explore the profile of Mateusz S Wietecha including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 273
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Recent Articles
1.
Sanger C, Cernakova M, Wietecha M, Garau Paganella L, Labouesse C, Dudaryeva O, et al.
Sci Adv . 2023 Aug; 9(35):eadh9219. PMID: 37647410
Hyperosmotic stress occurs in several diseases, but its long-term effects are largely unknown. We used sorbitol-treated human fibroblasts in 3D culture to study the consequences of hyperosmotic stress in the...
2.
Wietecha M, Lauenstein D, Cangkrama M, Seiler S, Jin J, Goppelt A, et al.
Matrix Biol . 2023 Mar; 119:19-56. PMID: 36914141
Healing wounds and cancers present remarkable cellular and molecular parallels, but the specific roles of the healing phases are largely unknown. We developed a bioinformatics pipeline to identify genes and...
3.
Wietecha M, Pensalfini M, Cangkrama M, Muller B, Jin J, Brinckmann J, et al.
Nat Commun . 2020 May; 11(1):2604. PMID: 32451392
Matrix deposition is essential for wound repair, but when excessive, leads to hypertrophic scars and fibrosis. The factors that control matrix deposition in skin wounds have only partially been identified...
4.
Hiebert P, Wietecha M, Cangkrama M, Haertel E, Mavrogonatou E, Stumpe M, et al.
Dev Cell . 2018 Jul; 46(2):145-161.e10. PMID: 30016619
Nrf2 is a key regulator of the antioxidant defense system, and pharmacological Nrf2 activation is a promising strategy for cancer prevention and promotion of tissue repair. Here we show, however,...
5.
Wietecha M, Krol M, Michalczyk E, Chen L, Gettins P, DiPietro L
Am J Physiol Heart Circ Physiol . 2015 Jul; 309(5):H812-26. PMID: 26163443
During dermal wound repair, hypoxia-driven proliferation results in dense but highly permeable, disorganized microvascular networks, similar to those in solid tumors. Concurrently, activated dermal fibroblasts generate an angiopermissive, provisional extracellular...
6.
Holman S, Wietecha M, Gullard A, Peterson J
J Dent Educ . 2014 Mar; 78(3):334-48. PMID: 24609336
This study aimed to provide a first nationwide assessment of dental students' attitudes toward the importance of research and its integration into the dental curriculum. For this purpose, the American...
7.
Wietecha M, DiPietro L
Adv Wound Care (New Rochelle) . 2014 Feb; 2(3):81-86. PMID: 24527330
Significance: Re-establishment of a functional vascular network is a critical component of successful wound repair. One of the most potent pro-angiogenic agents is vascular endothelial growth factor (VEGF), which, from...
8.
Wietecha M, Cerny W, DiPietro L
Curr Top Microbiol Immunol . 2012 Dec; 367:3-32. PMID: 23224648
Physiological angiogenesis refers to a naturally occurring process of blood vessel growth and regression, and it occurs as an integral component of tissue repair and regeneration. During wound healing, sprouting...
9.
Wietecha M, Chen L, Ranzer M, Anderson K, Ying C, Patel T, et al.
Am J Physiol Heart Circ Physiol . 2010 Nov; 300(2):H459-67. PMID: 21076020
Angiogenesis is regulated by signals received by receptor tyrosine kinases such as vascular endothelial growth factor receptors. Mammalian Sprouty (Spry) proteins are known to function by specifically antagonizing the activation...