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Mateusz Chmielarczyk

Explore the profile of Mateusz Chmielarczyk including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 68
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Recent Articles
1.
Szostakowska-Rodzos M, Chmielarczyk M, Zacharska W, Fabisiewicz A, Kurzyk A, Mysliwy I, et al.
Bioengineering (Basel) . 2025 Feb; 12(2). PMID: 40001667
The majority of the current cancer research is based on two-dimensional cell cultures and animal models. These methods have limitations, including different expressions of key factors involved in carcinogenesis and...
2.
Trebinska-Stryjewska A, Wakula M, Chmielarczyk M, Grzybowska E
Biochim Biophys Acta Mol Cell Res . 2023 Jul; 1870(7):119538. PMID: 37454914
HAX1 is a relatively small, ubiquitously expressed, predominantly mitochondrial, intrinsically disordered protein. It has been implicated in the regulation of apoptosis, cell migration, calcium cycling, proteostasis, angiogenesis, autophagy and translation....
3.
Balcerak A, Macech-Klicka E, Wakula M, Tomecki R, Goryca K, Rydzanicz M, et al.
Cells . 2022 Oct; 11(19). PMID: 36230905
HAX1 is a human protein with no known homologues or structural domains. Mutations in the gene cause severe congenital neutropenia through mechanisms that are poorly understood. Previous studies reported the...
4.
Kianfar M, Balcerak A, Chmielarczyk M, Tarnowski L, Grzybowska E
Int J Mol Sci . 2022 May; 23(9). PMID: 35563375
Entosis-a homotypic insertion of one cell into another, resulting in a death of the invading cell-has been described in many reports, but crucial aspects of its molecular mechanisms and clinical...
5.
Wakula M, Balcerak A, Rubel T, Chmielarczyk M, Konopinski R, Lyczek F, et al.
Biosci Rep . 2020 Nov; 40(11). PMID: 33146709
HCLS1-associated protein X-1 (HAX1) is a multifunctional protein involved in many cellular processes, including apoptosis, cell migration and calcium homeostasis, but its mode of action still remains obscure. Multiple HAX1...
6.
Wakula M, Balcerak A, Smietanka U, Chmielarczyk M, Konopinski R, Grzybowska E
J Vis Exp . 2020 Jul; (160). PMID: 32658197
The methods presented here quantify some parameters of confluent adherent cell monolayers from multiple appropriately stained confocal images: adhesion to the substrate as a function of the number and size...
7.
Balcerak A, Trebinska-Stryjewska A, Wakula M, Chmielarczyk M, Smietanka U, Rubel T, et al.
Mol Biol Cell . 2019 Oct; 30(25):3024-3036. PMID: 31644363
HAX1 protein is involved in the regulation of apoptosis, cell motility and calcium homeostasis. Its overexpression was reported in several tumors, including breast cancer. This study demonstrates that HAX1 has...
8.
Dziaman T, Ludwiczak H, Ciesla J, Banaszkiewicz Z, Winczura A, Chmielarczyk M, et al.
PLoS One . 2014 Dec; 9(12):e115558. PMID: 25526641
The ethiology of colon cancer is largely dependent on inflammation driven oxidative stress. The analysis of 8-oxodeoxyguanosine (8-oxodGuo) level in leukocyte DNA of healthy controls (138 individuals), patients with benign...
9.
Zayat V, Balcerak A, Korczynski J, Trebinska A, Wysocki J, Sarnowska E, et al.
DNA Cell Biol . 2014 Oct; 34(1):43-54. PMID: 25289648
HAX-1, a multifunctional protein involved in the regulation of apoptosis, cell migration, and calcium homeostasis, binds the 3' untranslated region motifs of specific transcripts. This suggests that HAX-1 plays a...