Massimo Gadina
Overview
Explore the profile of Massimo Gadina including associated specialties, affiliations and a list of published articles.
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115
Citations
8024
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Recent Articles
1.
Zorc R, Redmond C, Sylvester M, Maclean M, Yamamoto de Almeida L, Quinn K, et al.
Ann Rheum Dis
. 2025 Feb;
PMID: 40000263
Objectives: The study objective was to determine if a common single nucleotide polymorphism in the interleukin 6 (IL-6) receptor (rs2228145, p.Asp358Ala) predicted treatment response to tocilizumab in giant cell arteritis...
2.
Virtanen A, Spinelli F, Telliez J, OShea J, Silvennoinen O, Gadina M
Nat Rev Rheumatol
. 2024 Sep;
20(10):649-665.
PMID: 39251770
Cytokines function as communication tools of the immune system, serving critical functions in many biological responses and shaping the immune response. When cytokine production or their biological activity goes awry,...
3.
Oliveira C, Temesgen-Oyelakin Y, Naqi M, Davis M, Naz F, DellOrso S, et al.
Arthritis Rheumatol
. 2024 Jun;
76(10):1501-1511.
PMID: 38923259
Objective: Systemic lupus erythematosus (SLE) increases cardiovascular disease (CVD) risk, and this is not explained by traditional risk factors. Characterization of blood immunologic signatures that associate with subclinical CVD and...
4.
Gadina M, OShea J
Science
. 2024 Jun;
384(6702):1303-1304.
PMID: 38900897
Janus kinase (JAK) inhibitors improve antitumor responses.
5.
Oda H, Manthiram K, Pimpale Chavan P, Rieser E, Veli O, Kaya O, et al.
Nat Immunol
. 2024 Apr;
25(5):764-777.
PMID: 38609546
The linear ubiquitin assembly complex (LUBAC) consists of HOIP, HOIL-1 and SHARPIN and is essential for proper immune responses. Individuals with HOIP and HOIL-1 deficiencies present with severe immunodeficiency, autoinflammation...
6.
Lee W, Stone D, Hoffmann P, Rosenzweig S, Tsai W, Gadina M, et al.
Ann Rheum Dis
. 2024 Feb;
83(6):787-798.
PMID: 38408849
Objectives: To study the molecular pathogenesis of PAPA (pyogenic arthritis, pyoderma gangrenosum and acne) syndrome, a debilitating hereditary autoinflammatory disease caused by dominant mutation in . Methods: Gene knock-out and...
7.
Rosenstein R, Rose J, Brooks S, Tsai W, Gadina M, Pavletic S, et al.
JID Innov
. 2024 Feb;
4(2):100246.
PMID: 38357212
Cutaneous sclerotic chronic graft-versus-host disease (cGVHD) is a common and highly morbid complication of allogeneic hematopoietic stem cell transplantation. Our goals were to identify signals active in the skin of...
8.
Gutierrez-Rodrigues F, Wells K, Jones A, Hironaka D, Rankin C, Gadina M, et al.
Ann Rheum Dis
. 2023 Dec;
83(4):508-517.
PMID: 38049983
Objectives: Ageing and inflammation are associated with clonal haematopoiesis (CH), the emergence of somatic mutations in haematopoietic cells. This study details CH in patients with systemic vasculitis in association with...
9.
Castelo-Soccio L, Kim H, Gadina M, Schwartzberg P, Laurence A, OShea J
Nat Rev Immunol
. 2023 Nov;
24(1):79.
PMID: 38012368
No abstract available.
10.
Gadina M
Semin Arthritis Rheum
. 2023 Nov;
64S:152327.
PMID: 38007359
Background: Cytokines are soluble factors that affect host defense and maintain immune homeostasis. Altered cytokine production leads to a dysfunctional immune responses and immune-related diseases. Cytokines bind to specific receptors...