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Massimiliano Legnaro

Explore the profile of Massimiliano Legnaro including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 446
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Recent Articles
1.
Ferrari M, Sica E, De Bernardi F, Luini A, Legnaro M, Nosetti L, et al.
Cureus . 2024 Dec; 16(11):e74477. PMID: 39726493
Background: Obstructive sleep apnea syndrome (OSAS) is a chronic syndrome, affecting about 1%-5% of children. OSAS is characterized by increased resistance and collapse of the upper airways, with different degrees...
2.
Goncalves M, Furgiuele A, Rasini E, Legnaro M, Ferrari M, Luini A, et al.
Eur J Pharmacol . 2024 Feb; 968:176420. PMID: 38367683
Background: Proinflammatory cytokines powerfully induce the rate-limiting enzyme indoleamine 2, 3-dioxygenase-1 (IDO-1) in dendritic cells (DCs) and monocytes, it converts tryptophan (Trp) into L-kynurenine (KYN), along the kynurenine pathway (KP)....
3.
Ferrari M, Sica E, De Bernardi F, Luini A, Legnaro M, Nosetti L, et al.
Sleep Med . 2023 Dec; 114:82-85. PMID: 38157624
Background: Obstructive Sleep Apnea Syndrome (OSAS) affects approximately 1-5% of children and is linked to cardiovascular, metabolic, and neurobehavioral complications. Dysregulation of inflammatory process and sympathetic nervous system overstimulation leading...
4.
Furgiuele A, Marino F, Rasini E, Legnaro M, Luini A, Albizzati M, et al.
Int J Mol Sci . 2023 Oct; 24(19). PMID: 37834328
Cannabidiol (CBD), the main non-psychoactive component of L., is widely used in therapy for the treatment of different diseases and as an adjuvant drug. Our aim was to assess the...
5.
Cosentino M, Legnaro M, Luini A, Ferrari M, Sodergren M, Pacchetti B, et al.
Cannabis Cannabinoid Res . 2022 Aug; 8(6):999-1007. PMID: 35930236
In this study, the effects of the cannabinoid CBD were assessed on cyclooxygenase (COX)-1 and COX-2 expression and activity in resting and activated human neutrophils (polymorphonuclear [PMN] leukocytes). COX expression...
6.
Marino F, Pinoli M, Rasini E, Martini S, Luini A, Pulze L, et al.
Immunology . 2022 Jul; 167(4):508-527. PMID: 35897164
Dopamine (DA) affects immune functions in healthy subjects (HS) and during disease by acting on D1-like (D1 and D5) and D2-like (D2, D3 and D4) dopaminergic receptors (DR); however, its...
7.
De Francesco E, Terzaghi M, Storelli E, Magistrelli L, Comi C, Legnaro M, et al.
Mov Disord . 2020 Jul; 36(1):225-229. PMID: 32649001
Background: CD4+ T-cell dysregulation occurs in Parkinson's disease (PD); however, it is unknown whether it contributes to PD development. The objective of this study was to investigate transcription factor gene...
8.
Marino F, Cosentino M, Legnaro M, Luini A, Sigova J, Mocchi R, et al.
Dermatol Ther . 2020 Apr; 33(3):e13388. PMID: 32277559
Neauvia hydrogel (N-Gel) is a hyaluronic acid-based dermal filler, cross-linked with polyethylene glycol. This filler contains sodium hyaluronate at different concentrations, poly(ethylene glycol) diglycidyl ether cross-linked, glycine, and l-prolyne. Assessing...
9.
Coelho M, Imperatori A, Chiaravalli A, Franzi F, Castiglioni M, Rasini E, et al.
J Neuroimmune Pharmacol . 2019 Oct; 14(4):697-708. PMID: 31620969
Assessment of Beta-AR protein expression on tumour tissues might be a plausible strategy to select cancer patients who can benefit from Beta-blockers therapy. The aim of this study is to...
10.
Mabou Tagne A, Marino F, Legnaro M, Luini A, Pacchetti B, Cosentino M
Int J Mol Sci . 2019 Apr; 20(8). PMID: 31013912
Cannabis and cannabinoids offer significant therapeutic benefits for a wide scope of pathological conditions. Among them, the clinical issues rooted in inflammation stand out, nonetheless, the underlying mechanisms are not...