Masatoshi Hirayama
Overview
Explore the profile of Masatoshi Hirayama including associated specialties, affiliations and a list of published articles.
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Articles
58
Citations
851
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Recent Articles
1.
Morodomi S, Hirosue A, Rahman A, Nohata K, Matsuo M, Reda O, et al.
Cancer Med
. 2025 Feb;
14(4):e70544.
PMID: 39980140
Background: Virus-related cancers are malignancies caused by specific viruses, such as human papillomavirus (HPV), hepatitis B virus, and human T-cell leukemia virus, contributing significantly to the global cancer burden through...
2.
Sato S, Ogawa Y, Asai K, Shimizu E, Shimizu S, Taniguchi H, et al.
Sci Rep
. 2025 Feb;
15(1):4404.
PMID: 39910227
No abstract available.
3.
Hirayama M, Hatou S, Nomura M, Hokama R, Hirayama O, Inagaki E, et al.
Cell Rep Med
. 2025 Jan;
6(1):101847.
PMID: 39809262
A first-in-human investigator-initiated clinical study of a corneal endothelial cell substitute (CLS001) derived from a clinical-grade induced pluripotent stem cell (iPSC) line shows improvement of visual acuity and corneal stromal...
4.
Sato S, Ogawa Y, Asai K, Shimizu E, Shimizu S, Taniguchi H, et al.
Sci Rep
. 2025 Jan;
15(1):532.
PMID: 39748084
Systemic administration of Janus kinase (JAK) inhibitors is effective in treating chronic graft-versus-host disease (cGVHD) but is associated with side effects. Topical drug administration effectively minimizes side effects. We aimed...
5.
Sato S, Ogawa Y, Wong C, Le H, Yee R, Gombos D, et al.
Ocul Surf
. 2024 Oct;
34:477-488.
PMID: 39424225
Purpose: The topical administration of spironolactone, a mineralocorticoid receptor antagonist (MRA) improves dry eye symptoms in patients with ocular graft-versus-host disease (GVHD); however, the detailed mechanism remains unclear. This study...
6.
Asai K, Lee H, Sato S, Shimizu E, Jung J, Okazaki T, et al.
Invest Ophthalmol Vis Sci
. 2024 Aug;
65(10):38.
PMID: 39189995
Purpose: To identify molecular signatures specific for ocular graft-versus-host disease (GVHD) by proteomic analysis of corneas from mice with GVHD. Methods: We identified differentially expressed proteins (DEPs) in corneal samples...
7.
Sato S, Ogawa Y, Shimizu E, Asai K, Okazaki T, Rusch R, et al.
Ocul Surf
. 2024 Mar;
32:198-210.
PMID: 38499288
Purpose: Aging is a well-established risk factor for meibomian gland dysfunction (MGD). We previously reported an accelerated cellular senescence phenomenon in the lacrimal glands of a murine model of chronic...
8.
Hirayama M, Mure L, Le H, Panda S
iScience
. 2024 Feb;
27(3):109051.
PMID: 38384840
The hypothalamic suprachiasmatic nucleus (SCN) is composed of heterogenous populations of neurons that express signaling peptides such as vasoactive intestinal polypeptide (VIP) and arginine vasopressin (AVP) and regulate circadian rhythms...
9.
Shimmura S, Inagaki E, Hirayama M, Hatou S
Keio J Med
. 2024 Feb;
73(1):1-7.
PMID: 38369325
Regenerative medicine is a highly anticipated field with hopes to provide cures for previously uncurable diseases such as spinal cord injuries and retinal blindness. Most regenerative medical products use either...
10.
Sakakura S, Inagaki E, Sayano T, Yamazaki R, Fusaki N, Hatou S, et al.
Regen Ther
. 2023 Nov;
24:592-601.
PMID: 38034859
Introduction: Fuchs endothelial corneal dystrophy (FECD) is the leading cause of corneal blindness in developed countries. Corneal endothelial cells in FECD are susceptive to oxidative stress, leading to mitochondrial dysfunction...