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Masao Sasai

Explore the profile of Masao Sasai including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 94
Followers 0
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Recent Articles
1.
Handa K, Kawamura M, Sasai M, Matsuzaki T, Harada A, Fujimura L, et al.
J Control Release . 2025 Mar; :113623. PMID: 40073941
Messenger RNA (mRNA) has great potential to provide innovative medical solutions in the treatment of heart failure. Although lipid nanoparticles (LNPs) are an established mRNA delivery system, effectively delivering LNPs...
2.
Sakura K, Kuroyama M, Shintani Y, Funaki S, Atagi S, Kadota Y, et al.
Cancer Immunol Immunother . 2024 Oct; 73(12):243. PMID: 39358654
The hemagglutinating virus of Japan envelope (HVJ-E) is an inactivated Sendai virus particle with antitumor effect and inducing antitumor immunity. However, its dosage and efficacy have not been verified. We...
3.
Miyagawa S, Kawamura T, Ito E, Takeda M, Iseoka H, Yokoyama J, et al.
Stem Cell Res Ther . 2024 Mar; 15(1):73. PMID: 38475911
Background: Cell- or tissue-based regenerative therapy is an attractive approach to treat heart failure. A tissue patch that can safely and effectively repair damaged heart muscle would greatly improve outcomes...
4.
Shimatani K, Sato H, Mizukami K, Saito A, Sasai M, Enmi J, et al.
J Cardiovasc Transl Res . 2024 Feb; 17(4):828-841. PMID: 38376701
Critical limb ischemia (CLI) is a state of severe peripheral artery disease, with no effective treatment. Cell therapy has been investigated as a therapeutic tool for CLI, and pericytes are...
5.
Sasai M, Okamoto M, Tanigawa S, Okada S, Sugiyama D, Myoui A
Regen Ther . 2024 Jan; 25:85-91. PMID: 38187516
Introduction: The Act on the Safety of Regenerative Medicine enforced in Japan in 2014, regulates the manufacture of cellular processed products. However, with regards to the manufacturing facilities at medical...
6.
Kawamura T, Ito Y, Ito E, Takeda M, Mikami T, Taguchi T, et al.
Front Cardiovasc Med . 2023 Oct; 10:1182209. PMID: 37781295
Introduction: With the expected increase in patients with heart failure and ischemic 15 cardiomyopathy, the development of myocardial regenerative medicine using cell transplantation as a novel treatment method is progressing....
7.
Sakura K, Sasai M, Funaki S, Shintani Y, Okumura M, Kaneda Y
Cancers (Basel) . 2023 Feb; 15(3). PMID: 36765886
Malignant pleural mesothelioma (MPM) is a refractory tumor because most of the lesions are already disseminated at diagnosis. Previously, the main treatment for MPM was combination chemotherapy. However, recently, immune...
8.
Miyagawa S, Kainuma S, Kawamura T, Suzuki K, Ito Y, Iseoka H, et al.
Front Cardiovasc Med . 2022 Sep; 9:950829. PMID: 36051285
Despite major therapeutic advances, heart failure, as a non-communicable disease, remains a life-threatening disorder, with 26 million patients worldwide, causing more deaths than cancer. Therefore, novel strategies for the treatment...
9.
Nakazato T, Kawamura T, Uemura T, Liu L, Li J, Sasai M, et al.
Stem Cell Reports . 2022 Apr; 17(5):1170-1182. PMID: 35427484
A rotating wall vessel (RWV) bioreactor was constructed for growing massive functional cardiac constructs to recover the function of a distressed rat heart. Three-dimensional cardiac tissues were engineered by seeding...
10.
Sakura K, Sasai M, Mino T, Uyama H
Polymers (Basel) . 2022 Jan; 14(1). PMID: 35012190
The 5-year survival rate for pancreatic cancer remains low, and the development of new methods for its treatment is actively underway. After the surgical treatment of pancreatic cancer, recurrence and...