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Masahiko Obara

Explore the profile of Masahiko Obara including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 104
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Recent Articles
1.
Naya M, Aikawa T, Manabe O, Obara M, Koyanagawa K, Katoh C, et al.
Heart Vessels . 2021 Jan; 36(7):917-923. PMID: 33484293
Endothelin-1 contributes to the constrictor response of the coronary arteries in patients with ischemia with normal coronary arteries. There is thus increasing evidence that endothelin-1 plays a role in coronary...
2.
Aikawa T, Naya M, Koyanagawa K, Manabe O, Obara M, Magota K, et al.
Eur Heart J Cardiovasc Imaging . 2019 Sep; 21(1):36-46. PMID: 31544927
Aims: Myocardial perfusion imaging without and with quantitative myocardial blood flow (MBF) and myocardial flow reserve (MFR) plays an important role in the diagnosis and risk stratification of patients with...
3.
Aikawa T, Naya M, Obara M, Manabe O, Magota K, Koyanagawa K, et al.
Cardiovasc Res . 2018 Jul; 115(1):119-129. PMID: 29992275
Aims: Coronary flow reserve (CFR) is an integrated measure of the entire coronary vasculature, and is a powerful prognostic marker in coronary artery disease (CAD). The extent to which coronary...
4.
Obara M, Naya M, Oyama-Manabe N, Aikawa T, Tomiyama Y, Sasaki T, et al.
Medicine (Baltimore) . 2018 Jul; 97(27):e11354. PMID: 29979416
We have developed the method for dynamic 320-row multidetector computed tomography (MDCT)-derived quantitative coronary flow reserve (CFRCT) and hyperemic myocardial blood flow (MBFCT). We evaluated diagnostic value of CFRCT and...
5.
Hiroshima Y, Manabe O, Naya M, Tomiyama Y, Magota K, Obara M, et al.
J Nucl Cardiol . 2017 Dec; 27(4):1118-1125. PMID: 29270771
Background: C-hydroxyephedrine (HED) PET has been used to evaluate the myocardial sympathetic nervous system (SNS). Here we sought to establish a simultaneous approach for quantifying both myocardial blood flow (MBF)...
6.
Aikawa T, Naya M, Obara M, Oyama-Manabe N, Manabe O, Magota K, et al.
Eur J Nucl Med Mol Imaging . 2017 Jun; 44(11):1897-1905. PMID: 28653180
Purpose: This investigation aimed to identify significant predictors of regional sympathetic denervation quantified by C-hydroxyephedrine (HED) positron emission tomography (PET) in patients with heart failure with preserved left ventricular ejection...
7.
Manabe O, Naya M, Aikawa T, Obara M, Magota K, Kroenke M, et al.
EJNMMI Res . 2017 Jun; 7(1):52. PMID: 28585219
Background: The quantification of myocardial blood flow (MBF) and coronary flow reserve (CFR) are useful approaches for evaluating the functional severity of coronary artery disease (CAD). O-water positron emission tomography...
8.
Aikawa T, Oyama-Manabe N, Naya M, Ohira H, Sugimoto A, Tsujino I, et al.
Eur Radiol . 2017 Apr; 27(10):4054-4063. PMID: 28382537
Objectives: To evaluate the diagnostic value of delayed contrast-enhanced computed tomography (DE-CT) for cardiac sarcoidosis (CS) in patients with or without implantable devices, including a quantitative comparison with late gadolinium...
9.
Aikawa T, Naya M, Obara M, Manabe O, Tomiyama Y, Magota K, et al.
J Nucl Med . 2016 Nov; 58(5):784-790. PMID: 27811122
Diastolic dysfunction is important in the pathophysiology of heart failure with preserved ejection fraction (HFpEF). Sympathetic nervous hyperactivity may contribute to the development of diastolic dysfunction. The aim of this...
10.
Masuda A, Manabe O, Oyama-Manabe N, Naya M, Obara M, Sakakibara M, et al.
J Nucl Cardiol . 2015 Dec; 24(1):323-324. PMID: 26676029
No abstract available.