Masafumi Umekage
Overview
Explore the profile of Masafumi Umekage including associated specialties, affiliations and a list of published articles.
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10
Citations
946
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0
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Recent Articles
1.
Matsuo-Takasaki M, Kambayashi S, Hemmi Y, Wakabayashi T, Shimizu T, An Y, et al.
Elife
. 2024 Nov;
12.
PMID: 39529479
Human induced pluripotent stem cells (hiPSCs) are promising resources for producing various types of tissues in regenerative medicine; however, the improvement in a scalable culture system that can precisely control...
2.
Shimasaki N, Shimizu E, Nakamura Y, Iguchi H, Ueda A, Umekage M, et al.
Cytotherapy
. 2023 Sep;
25(12):1338-1348.
PMID: 37676216
Background Aims: Monocytes, derived from hematopoietic stem cells (HSCs), play a pivotal role in the immune response to cancer. Although they are an attractive source of cell therapy for cancer,...
3.
Yoshida S, Kato T, Sato Y, Umekage M, Ichisaka T, Tsukahara M, et al.
Med
. 2022 Nov;
4(1):51-66.e10.
PMID: 36395757
Background: Human induced pluripotent stem cells (iPSCs) are expected to be useful for regenerative medicine for many diseases. Many researchers have focused on and enabled the generation of differentiated cells...
4.
Kitano Y, Nishimura S, Kato T, Ueda A, Takigawa K, Umekage M, et al.
Mol Ther Methods Clin Dev
. 2022 Jun;
26:15-25.
PMID: 35755947
In order to expand the promise of regenerative medicine using allogeneic induced pluripotent stem cells (iPSCs), precise and efficient genome editing of human leukocyte antigen (HLA) genes would be advantageous...
5.
Doi D, Magotani H, Kikuchi T, Ikeda M, Hiramatsu S, Yoshida K, et al.
Nat Commun
. 2020 Jul;
11(1):3369.
PMID: 32632153
Induced pluripotent stem cell (iPSC)-derived dopaminergic (DA) neurons are an expected source for cell-based therapies for Parkinson's disease (PD). The regulatory criteria for the clinical application of these therapies, however,...
6.
Umekage M, Sato Y, Takasu N
Inflamm Regen
. 2019 Sep;
39:17.
PMID: 31497180
Induced pluripotent stem cells (iPSCs) can be produced from various somatic cells and have the ability to differentiate into various cells and tissues of the body. Regenerative medicine using iPSCs...
7.
Mandai M, Watanabe A, Kurimoto Y, Hirami Y, Morinaga C, Daimon T, et al.
N Engl J Med
. 2017 Mar;
376(11):1038-1046.
PMID: 28296613
We assessed the feasibility of transplanting a sheet of retinal pigment epithelial (RPE) cells differentiated from induced pluripotent stem cells (iPSCs) in a patient with neovascular age-related macular degeneration. The...
8.
Tonosaki M, Itoh K, Umekage M, Kishimoto T, Yaoi T, Lemmon V, et al.
PLoS One
. 2014 Feb;
9(1):e86186.
PMID: 24489698
L1cam (L1) is a cell adhesion molecule associated with a spectrum of human neurological diseases, the most well-known being X-linked hydrocephalus. Although we recently demonstrated that L1 plays an important...
9.
Kishimoto T, Itoh K, Umekage M, Tonosaki M, Yaoi T, Fukui K, et al.
J Neurosci Res
. 2012 Oct;
91(1):42-50.
PMID: 23073969
L1 is a cell adhesion molecule associated with a spectrum of human neurological diseases, the most well-known being X-linked hydrocephalus. L1 knockout (L1-KO) mice have revealed a variety of functions...
10.
Tozawa T, Itoh K, Yaoi T, Tando S, Umekage M, Dai H, et al.
Mol Neurobiol
. 2012 Jan;
45(2):287-97.
PMID: 22258561
Duchenne muscular dystrophy (DMD) causes cognitive impairment in one third of the patients, although the underlying mechanisms remain to be elucidated. Recent studies showed that mutations in the distal part...