Maryam F Afzali
Overview
Explore the profile of Maryam F Afzali including associated specialties, affiliations and a list of published articles.
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17
Citations
275
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Recent Articles
1.
Spittler A, Bukovec K, Afzali M, Leavell S, Bork S, Seebart C, et al.
Am J Vet Res
. 2025 Feb;
:1-12.
PMID: 39919377
Objective: To investigate indicators of mobility, inflammation, and cartilage remodeling in Dunkin-Hartley guinea pigs (Cavia porcellus) treated with manual acupuncture compared to 2 different comparator acupuncture groups. Methods: 12-month-old male...
2.
Afzali M, Sykes M, Burton L, Patton K, Lee K, Seebart C, et al.
Ann Transl Med
. 2024 Jun;
12(3):43.
PMID: 38911554
Background: Several tissues contribute to the onset and advancement of knee osteoarthritis (OA). One tissue type that is worthy of closer evaluation, particularly in the context of sex, is the...
3.
Timkovich A, Holling G, Afzali M, Kisiday J, Santangelo K
Connect Tissue Res
. 2023 Oct;
65(1):26-40.
PMID: 37898909
Purpose/aim: Cartilage injury and subsequent osteoarthritis (OA) are debilitating conditions affecting millions worldwide. As there are no cures for these ailments, novel therapies are needed to suppress disease pathogenesis. Given...
4.
Afzali M, Radakovich L, Sykes M, Campbell M, Patton K, Sanford J, et al.
Arthritis Res Ther
. 2022 Dec;
24(1):282.
PMID: 36578046
Background: The infrapatellar fat pad (IFP) is the largest adipose deposit in the knee; however, its contributions to the homeostasis of this organ remain undefined. To determine the influence of...
5.
Timkovich A, Sikes K, Andrie K, Afzali M, Sanford J, Fernandez K, et al.
Ann Biomed Eng
. 2022 Sep;
51(3):579-593.
PMID: 36070048
The anterior cruciate ligament (ACL) is the most commonly injured knee ligament. Surgical reconstruction is the gold standard treatment for ACL ruptures, but 20-50% of patients develop post-traumatic osteoarthritis (PTOA)....
6.
Afzali M, Pannone S, Martinez R, Campbell M, Sanford J, Pezzanite L, et al.
J Orthop Res
. 2022 Aug;
41(4):902-912.
PMID: 36030381
Osteoarthritis (OA) is a leading cause of morbidity among aging populations, yet symptom and/or disease-modification remains elusive. Adipose-derived mesenchymal stromal cells (adMSCs) have demonstrated immunomodulatory and anti-inflammatory properties that may...
7.
Musci R, Andrie K, Walsh M, Valenti Z, Linden M, Afzali M, et al.
J Physiol
. 2022 Aug;
601(11):2189-2216.
PMID: 35924591
Impaired mitochondrial function and disrupted proteostasis contribute to musculoskeletal dysfunction. However, few interventions simultaneously target these two drivers to prevent musculoskeletal decline. Nuclear factor erythroid 2-related factor 2 (Nrf2) activates...
8.
Wahl D, Moreno J, Santangelo K, Zhang Q, Afzali M, Walsh M, et al.
J Gerontol A Biol Sci Med Sci
. 2022 Mar;
77(9):1766-1774.
PMID: 35323931
Older age is the primary risk factor for most chronic diseases, including Alzheimer's disease (AD). Current preclinical models to study brain aging and AD are mainly transgenic and harbor mutations...
9.
Burton L, Afzali M, Radakovich L, Campbell M, Culver L, Olver C, et al.
Free Radic Biol Med
. 2021 Dec;
179:47-58.
PMID: 34923104
Iron has been emerging as a key contributor to aging-associated, chronic disorders due to the propensity for generating reactive oxygen species. To date, there are a limited number of publications...
10.
Spittler A, Afzali M, Bork S, Burton L, Radakovich L, Seebart C, et al.
PLoS One
. 2021 Jul;
16(7):e0253794.
PMID: 34242236
The Dunkin Hartley is the most common guinea pig strain used in biomedical research, particularly for studies of asthma, allergy, infectious disease, reproduction, and osteoarthritis. Minimally invasive blood tests, such...