Mary Prorok
Overview
Explore the profile of Mary Prorok including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
27
Citations
275
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Liu Z, Yu Z, Yu S, Zhu C, Dong M, Mao W, et al.
Mar Drugs
. 2021 Jan;
19(1).
PMID: 33478061
-methyl-D-aspartate receptor (NMDAR) antagonists have been found to be effective to inhibit morphine dependence. However, the discovery of the selective antagonist for NMDAR GluN2B with low side-effects still remains challenging....
2.
Dai Q, Dong M, Liu Z, Prorok M, Castellino F
J Inorg Biochem
. 2010 Dec;
105(1):52-7.
PMID: 21134602
We have previously elucidated a new paradigm for the metal ion-induced helix-helix assembly in the natural γ-carboxyglutamic acid (Gla)-containing class of conantokin (con) peptides, typified by con-G and a variant...
3.
Cnudde S, Prorok M, Jia X, Castellino F, Geiger J
J Biol Inorg Chem
. 2010 Nov;
16(2):257-66.
PMID: 21063741
The ability to form and control both secondary structure and oligomerization in short peptides has proven to be challenging owing to the structural instability of such peptides. The conantokin peptides...
4.
Llarrull L, Prorok M, Mobashery S
Biochemistry
. 2010 Aug;
49(37):7975-7.
PMID: 20722402
The expression of the gene products in many methicillin-resistant Staphylococcus aureus (MRSA) strains is regulated by the gene repressor BlaI. Here we show that BlaI is a mixture of monomer...
5.
Wang M, Prorok M, Castellino F
Biophys J
. 2010 Jul;
99(1):302-12.
PMID: 20655859
To gain insights into the mechanisms for the tight and highly specific interaction of the kringle 2 domain of human plasminogen (K2(Pg)) with a 30-residue internal peptide (VEK-30) from a...
6.
Cnudde S, Prorok M, Castellino F, Geiger J
J Biol Inorg Chem
. 2010 Mar;
15(5):667-75.
PMID: 20195692
Predatory sea snails from the Conus family produce a variety of venomous small helical peptides called conantokins that are rich in gamma-carboxyglutamic acid (Gla) residues. As potent and selective antagonists...
7.
Figuera-Losada M, Ranson M, Sanderson-Smith M, Walker M, Castellino F, Prorok M
Biochim Biophys Acta
. 2010 Feb;
1804(6):1342-9.
PMID: 20152941
In vertebrates, fibrinolysis is primarily carried out by the serine protease plasmin (Pm), which is derived from activation of the zymogen precursor, plasminogen (Pg). One of the most distinctive features...
8.
Wang M, Zajicek J, Geiger J, Prorok M, Castellino F
J Struct Biol
. 2009 Oct;
169(3):349-59.
PMID: 19800007
The solution structure of the complex containing the isolated kringle 2 domain of human plasminogen (K2(Pg)) and VEK-30, a 30-amino acid residue internal peptide from a streptococcal M-like plasminogen (Pg)...
9.
Dai Q, Xiao C, Dong M, Liu Z, Sheng Z, Castellino F, et al.
Peptides
. 2009 May;
30(5):866-72.
PMID: 19428763
We have previously found a new mode of metal ion-induced helix-helix assembly for the gamma-carboxyglutamate (Gla)-containing, neuroactive conantokin (con) peptides that is independent of the hydrophobic effect. In these unique...
10.
Sheng Z, Liang Z, Geiger J, Prorok M, Castellino F
Neuropharmacology
. 2009 May;
57(2):127-36.
PMID: 19427876
The conantokins are short, naturally occurring peptides that inhibit ion flow through N-methyl-d-aspartate receptor (NMDAR) channels. One member of this peptide family, conantokin-G (con-G), shows high selectivity for antagonism of...