Martine Hascoet
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Explore the profile of Martine Hascoet including associated specialties, affiliations and a list of published articles.
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31
Citations
936
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Recent Articles
1.
Bourin M, Hascoet M
Behav Brain Res
. 2009 Dec;
208(2):352-8.
PMID: 20006646
Unlabelled: Etifoxine is an anxiolytic compound structurally unrelated to benzodiazepine and neurosteroids but potentiating GABA(A) receptor function by a dual mode of action including a direct positive allosteric modulation through...
2.
Bourin M, Chenu F, Hascoet M
Curr Drug Targets
. 2009 Aug;
10(11):1052-60.
PMID: 19702557
Antidepressant drugs modify in different ways the activity of neurons, by increasing monoamines levels and by modulating ion channels. Sodium channels are molecular targets for antiepileptic drugs, which can also...
3.
Bourin M, Chenu F, Hascoet M
Behav Brain Res
. 2009 Aug;
205(2):421-5.
PMID: 19660501
Unlabelled: Topiramate and phenytoin possess mood stabilizing properties. The mechanism of action of anticonvulsants used in the treatment of bipolar depression is complex and still not completely elucidated. Na(+) channels...
4.
Petit-Demouliere B, Masse F, Cogrel N, Hascoet M, Bourin M
Behav Brain Res
. 2009 Jun;
204(1):200-5.
PMID: 19523493
Four-plate test-retest (FPT-R) is a useful tool to study aversive memory and abolishment of benzodiazepine effects in experienced mice to four-plate test (FPT), namely one-trial tolerance. In the present study,...
5.
Bourin M, Chenu F, Prica C, Hascoet M
Psychopharmacology (Berl)
. 2009 Jun;
206(1):97-107.
PMID: 19517098
Rationale: A deficiency in brain monoamine systems (serotonin, dopamine, and/or norepinephrine) have long been hypothesized for the pathogenesis of depression. Drugs enhancing neurotransmission of those monoamines have been proven to...
6.
Prica C, Hascoet M, Bourin M
Behav Brain Res
. 2008 Jul;
194(1):92-9.
PMID: 18647622
Unlabelled: The monoamine hypothesis based on the deficiency of one or several monoamines is commonly evoked to explain the physiopathology of depression. This hypothesis initially based on noradrenalin and serotonin...
7.
Prica C, Hascoet M, Bourin M
Behav Brain Res
. 2008 Apr;
191(1):49-54.
PMID: 18433891
Unlabelled: Lamotrigine has been found to be efficacious in the acute management of bipolar depression and long-term management of bipolar disorder, especially in delaying depressive recurrence, either as monotherapy or...
8.
Masse F, Petit-Demouliere B, Dubois I, Hascoet M, Bourin M
Behav Brain Res
. 2007 Dec;
188(2):291-7.
PMID: 18155304
Anxiolytic-like effects of DOI, a 5-HT(2A/2C) agonist have been observed in the four plates test (FPT) after intra-peritoneal administrations. In the present study, DOI (1 microg, 2 microg or 5...
9.
Bourin M, Petit-Demouliere B, Dhonnchadha B, Hascoet M
Fundam Clin Pharmacol
. 2007 Nov;
21(6):567-74.
PMID: 18034657
Among the multiple possibilities to study human pathologies, animal models remain one of the most used pathways. They allow to access to unavailable answers in human patients and to learn...
10.
Masse F, Hascoet M, Bourin M
Eur Neuropsychopharmacol
. 2007 Jan;
17(6-7):483-91.
PMID: 17196374
5-HTergic and GABAergic systems are involved in neurobiology of anxiety. Precedent studies have demonstrated that SSRIs possessed an anxiolytic-like effect in the four-plate test (FPT) at doses that did not...