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Martin Maly

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Citations 368
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Recent Articles
1.
Babai K, Long F, Maly M, Yamashita K, Murshudov G
Acta Crystallogr D Struct Biol . 2024 Dec; 80(Pt 12):821-833. PMID: 39625466
Metals are essential components for the structure and function of many proteins. However, accurate modelling of their coordination environments remains a challenge due to the complexity and diversity of metal-coordination...
2.
Cordery C, Craddock J, Maly M, Basavaraja K, Webb J, Walsh M, et al.
RSC Chem Biol . 2024 Sep; PMID: 39247681
The switch between planktonic and biofilm lifestyle correlates with intracellular concentration of the second messenger bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP). While bacteria possess cyclase and phosphodiesterase enzymes to catalyse formation...
3.
Maly M, Kucerka O, Bechynska K, Koci K, Mandys V, Hajslova J, et al.
Vascul Pharmacol . 2024 May; 155:107377. PMID: 38705432
Background: Atherosclerosis is a major cause of ischemic stroke, and early detection of advanced atherosclerosis in the carotid artery is important for reducing morbidity and mortality. What is even more...
4.
Kucerka O, Blahutova M, Kosek V, Minarikova P, Horacek J, Urbanek P, et al.
Metabolites . 2024 Apr; 14(4). PMID: 38668313
Inflammatory bowel disease, encompassing Crohn's disease and ulcerative colitis, is a persistent immune-mediated inflammatory gastrointestinal disease. This study investigates the role of growth differentiation factor 15 in severe IBD cases,...
5.
Bolton R, Machelett M, Stubbs J, Axford D, Caramello N, Catapano L, et al.
Proc Natl Acad Sci U S A . 2024 Mar; 121(12):e2308478121. PMID: 38489389
The marine cyanobacterium is a main contributor to global photosynthesis, whilst being limited by iron availability. Cyanobacterial genomes generally encode two different types of FutA iron-binding proteins: periplasmic FutA2 ABC...
6.
Mengozzi L, Barison I, Maly M, Lorenzoni G, Fedrigo M, Castellani C, et al.
Stroke . 2024 Mar; 55(4):963-971. PMID: 38465650
Background: Thrombosis is linked to neutrophil release of neutrophil extracellular traps (NETs). NETs are proposed as a mechanism of resistance to thrombolysis. This study intends to analyze the composition of...
7.
Stubbs J, Hornsey T, Hanrahan N, Esteban L, Bolton R, Maly M, et al.
IUCrJ . 2024 Mar; 11(Pt 2):237-248. PMID: 38446456
Serial crystallography requires large numbers of microcrystals and robust strategies to rapidly apply substrates to initiate reactions in time-resolved studies. Here, we report the use of droplet miniaturization for the...
8.
Kolenko P, Mikulecky P, Pham P, Maly M, Schneider B
J Appl Crystallogr . 2023 Aug; 56(Pt 4):1261-1266. PMID: 37555209
Binder H33 is a small protein binder engineered by ribosome display to bind human interleukin 10. Crystals of binder H33 display severe diffraction anisotropy. A set of data files with...
9.
Maly M, Kolenko P, Stransky J, Svecova L, Duskova J, Koval T, et al.
Acta Crystallogr F Struct Biol Commun . 2023 Jul; 79(Pt 7):180-192. PMID: 37405486
The resistance of the emerging human pathogen Stenotrophomonas maltophilia to tetracycline antibiotics mainly depends on multidrug efflux pumps and ribosomal protection enzymes. However, the genomes of several strains of this...
10.
Agirre J, Atanasova M, Bagdonas H, Ballard C, Basle A, Beilsten-Edmands J, et al.
Acta Crystallogr D Struct Biol . 2023 Jun; 79(Pt 6):449-461. PMID: 37259835
The Collaborative Computational Project No. 4 (CCP4) is a UK-led international collective with a mission to develop, test, distribute and promote software for macromolecular crystallography. The CCP4 suite is a...