Martin Javors
Overview
Explore the profile of Martin Javors including associated specialties, affiliations and a list of published articles.
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28
Citations
1482
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Recent Articles
1.
Martinez P, Martinez V, Rani S, Murrell M, Javors M, Gelfond J, et al.
Brain Behav
. 2023 Jul;
13(9):e3150.
PMID: 37452461
Introduction: The discovery of biogenic aldehydes in the postmortem parkinsonian brain and the ability of these aldehydes to modify and cross-link proteins has called attention to their possible role in...
2.
Wickline J, Smith S, Shin R, Odfalk K, Sanchez J, Javors M, et al.
Neuropharmacology
. 2023 Feb;
227():109454.
PMID: 36740015
Epidemiological studies suggest that L-type calcium channel (LTCC) antagonists may reduce the incidence of age-associated neurodegenerative diseases including Alzheimer's disease (AD). However, the neuroprotective mechanism of LTCC antagonists is unknown....
3.
Salmon A, Nelson J, Gelfond J, Javors M, Ginsburg B, Lopez-Cruzan M, et al.
Geroscience
. 2021 Jul;
43(5):2105-2118.
PMID: 34240333
With evolving cores, enrichment and training programs, and supported research projects, the San Antonio (SA) Nathan Shock Center has for 26 years provided critical support to investigators locally, nationally, and...
4.
Laberge R, Sun Y, Orjalo A, Patil C, Freund A, Zhou L, et al.
Nat Cell Biol
. 2021 Apr;
23(5):564-565.
PMID: 33824512
No abstract available.
5.
Fraser E, Hill-Kapturczak N, Jett J, Beck R, Oluwoye O, Kriegel L, et al.
Contemp Clin Trials Commun
. 2021 Mar;
22:100757.
PMID: 33763620
Background: Contingency management (CM) is an intervention where incentives are provided in exchange for biochemically confirmed alcohol abstinence. CM is effective at initiating alcohol abstinence, but it is less effective...
6.
Ji N, Mukherjee N, Reyes R, Gelfond J, Javors M, Meeks J, et al.
J Immunother Cancer
. 2021 Mar;
9(3).
PMID: 33653802
Background: Although intravesical BCG is the standard treatment of high-grade non-muscle invasive bladder cancer (NMIBC), response rates remain unsatisfactory. In preclinical models, rapamycin enhances BCG vaccine efficacy against tuberculosis and...
7.
Dodds S, Parihar M, Javors M, Nie J, Musi N, Sharp Z, et al.
Aging Cell
. 2020 Jan;
19(2):e13088.
PMID: 31903726
Acarbose blocks the digestion of complex carbohydrates, and the NIA Intervention Testing Program (ITP) found that it improved survival when fed to mice. Yet, we do not know if lifespan...
8.
Fernandez E, Ross C, Liang H, Javors M, Tardif S, Salmon A
Pathobiol Aging Age Relat Dis
. 2019 Sep;
9(1):1657756.
PMID: 31497263
Metformin has beneficial effects on several age-related diseases (e.g., diabetes, obesity, cancer) and extends lifespan in nematodes and mice. Acarbose, an FDA-approved agent for treating type 2 diabetes, prevents breakdown...
9.
Miller R, Harrison D, Astle C, Bogue M, Brind J, Fernandez E, et al.
Aging Cell
. 2019 Mar;
18(3):e12953.
PMID: 30916479
Diets low in methionine extend lifespan of rodents, though through unknown mechanisms. Glycine can mitigate methionine toxicity, and a small prior study has suggested that supplemental glycine could extend lifespan...
10.
Svatek R, Ji N, de Leon E, Mukherjee N, Kabra A, Hurez V, et al.
Cancer Immunol Res
. 2018 Dec;
7(3):466-475.
PMID: 30563829
The mechanistic target of rapamycin (mTOR) integrates environmental inputs to regulate cellular growth and metabolism in tumors. However, mTOR also regulates T-cell differentiation and activation, rendering applications of mTOR inhibitors...