Martin Guthold
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Explore the profile of Martin Guthold including associated specialties, affiliations and a list of published articles.
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44
Citations
543
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Recent Articles
1.
Patel C, Wiele S, Kim L, Payne E, Bruno-Garcia M, Devorak A, et al.
Life Sci Space Res (Amst)
. 2025 Jan;
44():67-78.
PMID: 39864914
Reduced weight-bearing during spaceflight has been associated with musculoskeletal degradation that risks astronaut health and performance in transit and upon reaching deep space destinations. Previous rodent experiments aboard the international...
2.
Alharbi N, Guthold M
J Mech Behav Biomed Mater
. 2024 May;
155:106564.
PMID: 38749267
Polycaprolactone (PCL) nanofibers are a promising material for biomedical applications due to their biocompatibility, slow degradation rate, and thermal stability. We electrospun PCL fibers onto a striated substrate with 12 ...
3.
Hur W, Kawano T, Mwiza J, Paul D, Lee R, Clark E, et al.
Blood
. 2023 Oct;
143(2):105-117.
PMID: 37832029
Elevated circulating fibrinogen levels correlate with increased risk for both cardiovascular and venous thromboembolic diseases. In vitro studies show that formation of a highly dense fibrin matrix is a major...
4.
Belcher H, Guthold M, Hudson N
Res Pract Thromb Haemost
. 2023 Aug;
7(5):100285.
PMID: 37601015
Background: Altered fibrin fiber structure is linked to pathologic states, including coronary heart disease, ischemic stroke, and atherosclerosis. However, several different techniques are commonly utilized for studying fibrin structures, and...
5.
Alharbi N, Brigham A, Guthold M
Nanomaterials (Basel)
. 2023 Apr;
13(8).
PMID: 37110944
Electrospinning is a process to produce versatile nanoscale fibers. In this process, synthetic and natural polymers can be combined to produce novel, blended materials with a range of physical, chemical,...
6.
Belcher H, Litwa K, Guthold M, Hudson N
Biomolecules
. 2022 Jun;
12(6).
PMID: 35740932
Turbidimetry is an experimental technique often used to study the structure of filamentous networks. To extract structural properties such as filament diameter from turbidimetric data, simplifications to light scattering theory...
7.
Popovic G, Kirby N, Dement T, Peterson K, Daub C, Belcher H, et al.
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35162976
Fibrin forms the structural scaffold of blood clots and has great potential for biomaterial applications. Creating recombinant expression systems of fibrinogen, fibrin's soluble precursor, would advance the ability to construct...
8.
Daraei A, Pieters M, Baker S, de Lange-Loots Z, Siniarski A, Litvinov R, et al.
Biomolecules
. 2021 Oct;
11(10).
PMID: 34680169
Scanning Electron Microscopy (SEM) is a powerful, high-resolution imaging technique widely used to analyze the structure of fibrin networks. Currently, structural features, such as fiber diameter, length, density, and porosity,...
9.
Maksudov F, Daraei A, Sesha A, Marx K, Guthold M, Barsegov V
Acta Biomater
. 2021 Oct;
136:327-342.
PMID: 34606991
Structural mechanisms underlying the mechanical properties of fibrin fibers are elusive. We combined tensile testing of uncrosslinked fibrin polymers in vitro and in silico to explore their material properties. The...
10.
Lee H, Bonin K, Guthold M
Biochim Biophys Acta Gen Subj
. 2021 Mar;
1865(6):129891.
PMID: 33689830
Background: The epithelium forms a protective barrier against external biological, chemical and physical insults. So far, AFM-based, micro-mechanical measurements have only been performed on single cells and confluent cells, but...