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Martin Duddy

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Articles 39
Citations 1706
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Recent Articles
1.
Blackstone J, Williams T, Nicholas J, Bordea E, De Angelis F, Bianchi A, et al.
BMJ Open . 2024 Sep; 14(9):e086414. PMID: 39284697
Introduction: There remains a high unmet need for disease-modifying therapies that can impact disability progression in secondary progressive multiple sclerosis (SPMS). Following positive results of the phase 2 MS-STAT study,...
2.
John N, Li Y, De Angelis F, Stutters J, Carrasco F, Eshaghi A, et al.
BMJ Neurol Open . 2024 Sep; 6(2):e000670. PMID: 39262426
Background: The brain reserve hypothesis posits that larger maximal lifetime brain growth (MLBG) may confer protection against physical disability in multiple sclerosis (MS). Larger MLBG as a proxy for brain...
3.
Paranathala M, Mills R, Rai P, Pavese N, Hussain M, Duddy M, et al.
Br J Neurosurg . 2023 Nov; :1-6. PMID: 37937771
Introduction: Tremor is a disabling symptom of multiple sclerosis (MS), with limited treatment modalities. Thalamic ventral-intermediate-nucleus (VIM) deep brain stimulation (DBS) is a method of neuromodulation. We describe the long-term...
4.
Anderson K, Warren N, Duddy M, McKean P, Miller J
Pract Neurol . 2022 Jan; 22(3):209-212. PMID: 35074798
It is increasingly common for secondary care to provide advice to primary care without an outpatient appointment. Even before the increased telemedicine during COVID-19, many hospital services gave advice alone...
5.
Filippi M, Danesi R, Derfuss T, Duddy M, Gallo P, Gold R, et al.
J Neurol . 2021 Oct; 269(3):1670-1677. PMID: 34626224
Early intervention with high-efficacy disease-modifying therapy (HE DMT) may be the best strategy to delay irreversible neurological damage and progression of multiple sclerosis (MS). In European healthcare systems, however, patient...
6.
Rodgers J, Friede T, Vonberg F, Constantinescu C, Coles A, Chataway J, et al.
Brain . 2021 Oct; 145(4):1368-1378. PMID: 34623418
The negative impact of smoking in multiple sclerosis is well established; however, there is much less evidence as to whether smoking cessation is beneficial to progression in multiple sclerosis. Adults...
7.
Duddy M, Wilkinson C, Medhurst S, Rhys K
Mult Scler Relat Disord . 2021 Aug; 55:103174. PMID: 34399317
Background: Recognising the transition from relapsing remitting multiple sclerosis (RRMS) to secondary progressive MS (SPMS) in clinical practice can be challenging. With disease-modifying therapies (DMTs) commonly used for RRMS accepted...
8.
Garjani A, Middleton R, Hunter R, Tuite-Dalton K, Coles A, Dobson R, et al.
Mult Scler Relat Disord . 2021 May; 52:102939. PMID: 34010764
Background: Infections can trigger exacerbations of multiple sclerosis (MS). The effects of the coronavirus disease 2019 (COVID-19) on MS are not known. The aim of this study was to understand...
9.
Ellison P, Goodall S, Kennedy N, Dawes H, Clark A, Pomeroy V, et al.
Neuropsychol Rev . 2021 May; 32(3):506-519. PMID: 33961198
Fatigue is one of the most debilitating symptoms for people with multiple sclerosis (PwMS). By consolidating a diverse and conflicting evidence-base, this systematic review and meta-analysis aimed to gain new...
10.
Torkildsen O, Linker R, Sesmero J, Fantaccini S, Sanchez-de la Rosa R, De Seze J, et al.
Neurodegener Dis Manag . 2020 Nov; 11(1):9-19. PMID: 33234006
The transition from relapsing-remitting multiple sclerosis to secondary progressive multiple sclerosis (SPMS) remains a clinical challenge owing to the heterogeneous course of the disease, indistinct disease progression and lack of...