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Martin Bernhard Dorner

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Recent Articles
1.
Gao L, Nowakowska M, Selby K, Przykopanski A, Chen B, Kruger M, et al.
Nat Struct Mol Biol . 2025 Jan; PMID: 39838108
Botulinum neurotoxins (BoNTs) rank among the most potent toxins and many of them are produced by bacteria carrying the orfX gene cluster that also encodes four nontoxic proteins (OrfX1, OrfX2,...
2.
Dorner M, Wilking H, Skiba M, Wilk L, Steinberg M, Worbs S, et al.
Euro Surveill . 2023 Jun; 28(23). PMID: 37289431
In March 2023, 34 associated cases of iatrogenic botulism were detected in Germany (30 cases), Switzerland (two cases), Austria (one case), and France (one case). An alert was rapidly disseminated...
3.
Hendrickx D, Varela Martinez C, Contzen M, Wagner-Wiening C, Janke K, Hernando Jimenez P, et al.
Front Public Health . 2023 Jan; 10:1039770. PMID: 36684858
Botulism outbreaks due to commercial products are extremely rare in the European Union. Here we report on the first international outbreak of foodborne botulism caused by commercial salt-cured, dried roach...
4.
von Berg L, Stern D, Weisemann J, Rummel A, Dorner M, Dorner B
Toxins (Basel) . 2019 Oct; 11(10). PMID: 31614566
The detection of catalytically active botulinum neurotoxins (BoNTs) can be achieved by monitoring the enzymatic cleavage of soluble NSF (N-ethylmaleimide-sensitive-factor) attachment protein receptor (SNARE) proteins by the toxins' light chains...
5.
Stern D, Weisemann J, Le Blanc A, von Berg L, Mahrhold S, Piesker J, et al.
PLoS Pathog . 2018 May; 14(5):e1007048. PMID: 29718991
The exceptional toxicity of botulinum neurotoxins (BoNTs) is mediated by high avidity binding to complex polysialogangliosides and intraluminal segments of synaptic vesicle proteins embedded in the presynaptic membrane. One peculiarity...