Marthe T Maehlen
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Explore the profile of Marthe T Maehlen including associated specialties, affiliations and a list of published articles.
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9
Citations
74
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Recent Articles
1.
Guderud K, Sunde L, Flam S, Maehlen M, Mjaavatten M, Norli E, et al.
Front Immunol
. 2021 Dec;
12:713611.
PMID: 34867944
Background: Methotrexate (MTX) is the first line treatment of rheumatoid arthritis (RA), and methylation changes in bulk T cells have been reported after treatment with MTX. We have investigated cell-type...
2.
Gansmo L, Lie B, Maehlen M, Vatten L, Romundstad P, Hveem K, et al.
Gene
. 2021 Jun;
793:145747.
PMID: 34077778
Background: In addition to being a tumour suppressor, TP53 is a suppressor of inflammation, and dysfunction of this gene has been related to autoimmune diseases. Patients with autoimmunity, such as...
3.
Heinicke F, Zhong X, Flam S, Breidenbach J, Leithaug M, Maehlen M, et al.
Front Immunol
. 2021 Apr;
12:663736.
PMID: 33897713
Rheumatoid arthritis (RA) is a complex disease with a wide range of underlying susceptibility factors. Recently, dysregulation of microRNAs (miRNAs) in RA have been reported in several immune cell types...
4.
Guderud K, Sunde L, Flam S, Maehlen M, Mjaavatten M, Lillegraven S, et al.
Front Immunol
. 2020 Mar;
11:194.
PMID: 32117312
Differences in DNA methylation have been reported in B and T lymphocyte populations, including CD4 T cells, isolated from rheumatoid arthritis (RA) patients when compared to healthy controls. CD4 T...
5.
Shahram F, Maehlen M, Akhlaghi M, Davatchi F, Liao Y, Weyand C
Eur J Rheumatol
. 2019 Jul;
6(4):199-206.
PMID: 31329543
Objective: Behçet's disease (BD) is a rare vasculitis that results in multi-organ inflammatory disease. At-risk populations are most prevalent in the Middle East and East Asia. Clinical data on BD...
6.
Maehlen M, Olsen I, Andreassen B, Viken M, Jiang X, Alfredsson L, et al.
Ann Rheum Dis
. 2013 Dec;
74(4):762-8.
PMID: 24336335
Objective: Certain HLA-DRB1 alleles and single-nucleotide polymorphisms (SNPs) are associated with rheumatoid arthritis (RA). Our objective was to examine the combined effect of these associated variants, calculated as a cumulative...
7.
Nordang G, Flam S, Maehlen M, Kvien T, Viken M, Lie B
Rheumatology (Oxford)
. 2013 Aug;
52(11):1973-82.
PMID: 23901134
Objective: The MHC exerts the greatest contribution to RA susceptibility, where certain HLA-DRB1 alleles confer the greatest risk. Interestingly, there is evidence for more risk factors in the MHC with...
8.
Maehlen M, Provan S, de Rooy D, van der Helm-van Mil A, Krabben A, Saxne T, et al.
PLoS One
. 2013 Apr;
8(4):e60970.
PMID: 23613766
Objective: Apolipoprotein E (APOE) genotypes are associated with cardiovascular disease (CVD) and lipid levels. In rheumatoid arthritis (RA), an association has been found with disease activity. We examined the associations...
9.
Maehlen M, Nordang G, Syversen S, van der Heijde D, Kvien T, Uhlig T, et al.
J Rheumatol
. 2011 Sep;
38(11):2329-35.
PMID: 21885492
Objective: Studies of Caucasian populations have shown conflicting results concerning the association between a promoter polymorphism -169T>C of the Fc receptor-like 3 (FCRL3) gene and rheumatoid arthritis (RA). It is...