Marten A Siemelink
Overview
Explore the profile of Marten A Siemelink including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
202
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0
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Recent Articles
1.
van der Laan S, Siemelink M, Haitjema S, Asl H, Perisic L, Mokry M, et al.
Circ Genom Precis Med
. 2018 Oct;
11(9):e002115.
PMID: 30354329
Background: Atherosclerosis is a chronic inflammatory disease in part caused by lipid uptake in the vascular wall, but the exact underlying mechanisms leading to acute myocardial infarction and stroke remain...
2.
Siemelink M, van der Laan S, Haitjema S, van Koeverden I, Schaap J, Wesseling M, et al.
Circ Genom Precis Med
. 2018 Oct;
11(9):e002030.
PMID: 30354327
Background: Tobacco smoking is a major risk factor for atherosclerotic disease and has been associated with DNA methylation (DNAm) changes in blood cells. However, whether smoking influences DNAm in the...
3.
Justice A, Winkler T, Feitosa M, Graff M, Fisher V, Young K, et al.
Nat Commun
. 2017 Apr;
8:14977.
PMID: 28443625
Few genome-wide association studies (GWAS) account for environmental exposures, like smoking, potentially impacting the overall trait variance when investigating the genetic contribution to obesity-related traits. Here, we use GWAS data...
4.
Pasterkamp G, van der Laan S, Haitjema S, Asl H, Siemelink M, Bezemer T, et al.
Arterioscler Thromb Vasc Biol
. 2016 Apr;
36(6):1240-6.
PMID: 27079880
Objective: The genetically modified mouse is the most commonly used animal model for studying the pathogenesis of atherosclerotic disease. We aimed to assess if mice atherosclerosis-related genes could be validated...
5.
Hagg S, Ganna A, van der Laan S, Esko T, Pers T, Locke A, et al.
Hum Mol Genet
. 2015 Sep;
24(23):6849-60.
PMID: 26376864
To date, genome-wide association studies (GWASs) have identified >100 loci with single variants associated with body mass index (BMI). This approach may miss loci with high allelic heterogeneity; therefore, the...
6.
Schadenberg A, van den Broek T, Siemelink M, Algra S, de Jong P, Jansen N, et al.
J Allergy Clin Immunol
. 2013 Oct;
133(1):277-80.e1-6.
PMID: 24139831
No abstract available.