Marta J Gonzalez-Hernandez
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Explore the profile of Marta J Gonzalez-Hernandez including associated specialties, affiliations and a list of published articles.
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10
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519
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Recent Articles
1.
Contreras-Galindo R, Kaplan M, Dube D, Gonzalez-Hernandez M, Chan S, Meng F, et al.
J Virol
. 2015 May;
89(14):7187-201.
PMID: 25926654
Unlabelled: Human endogenous retroviruses (HERV) make up 8% of the human genome. While the youngest of these retroviruses, HERV-K(HML-2), termed HK2, is able to code for all viral proteins and...
2.
Charbonneau M, Gonzalez-Hernandez M, Showalter H, Donato N, Wobus C, ORiordan M
PLoS One
. 2014 Aug;
9(8):e104096.
PMID: 25093325
The global spread of anti-microbial resistance requires urgent attention, and diverse alternative strategies have been suggested to address this public health concern. Host-directed immunomodulatory therapies represent one approach that could...
3.
Dube D, Contreras-Galindo R, He S, King S, Gonzalez-Hernandez M, Gitlin S, et al.
J Virol
. 2014 Jun;
88(17):9673-82.
PMID: 24920813
Unlabelled: Human endogenous retrovirus type K (HERV-K) proviruses are scattered throughout the human genome, but as no infectious HERV-K virus has been detected to date, the mechanism by which these...
4.
Gonzalez-Hernandez M, Cavalcoli J, Sartor M, Contreras-Galindo R, Meng F, Dai M, et al.
J Virol
. 2014 May;
88(16):8924-35.
PMID: 24872592
Unlabelled: Approximately 8% of the human genome is made up of endogenous retroviral sequences. As the HIV-1 Tat protein activates the overall expression of the human endogenous retrovirus type K...
5.
Gonzalez-Hernandez M, Pal A, Gyan K, Charbonneau M, Showalter H, Donato N, et al.
PLoS One
. 2014 Apr;
9(4):e94491.
PMID: 24722666
Most antiviral treatment options target the invading pathogen and unavoidably encounter loss of efficacy as the pathogen mutates to overcome replication restrictions. A good strategy for circumventing drug resistance, or...
6.
Contreras-Galindo R, Kaplan M, He S, Contreras-Galindo A, Gonzalez-Hernandez M, Kappes F, et al.
Genome Res
. 2013 May;
23(9):1505-13.
PMID: 23657884
Human endogenous retroviruses (HERVs) make up 8% of the human genome. The HERV-K (HML-2) family is the most recent group of these viruses to have inserted into the genome, and...
7.
Mor-Vaknin N, Legendre M, Yu Y, Serezani C, Garg S, Jatzek A, et al.
Sci Rep
. 2013 Jan;
3:1045.
PMID: 23304436
Vimentin, an abundant intermediate filament protein, presumably has an important role in stabilizing intracellular architecture, but its function is otherwise poorly understood. In a vimentin knockout (Vim KO) mouse model,...
8.
Gonzalez-Hernandez M, Swanson M, Contreras-Galindo R, Cookinham S, King S, Noel Jr R, et al.
J Virol
. 2012 May;
86(15):7790-805.
PMID: 22593154
Human endogenous retroviruses (HERVs) make up 8% of the human genome. The expression of HERV-K (HML-2), the family of HERVs that most recently entered the genome, is tightly regulated but...
9.
Contreras-Galindo R, Kaplan M, Contreras-Galindo A, Gonzalez-Hernandez M, Ferlenghi I, Giusti F, et al.
J Virol
. 2011 Oct;
86(1):262-76.
PMID: 22031938
We previously reported finding the RNA of a type K human endogenous retrovirus, HERV-K (HML-2), at high titers in the plasma of HIV-1-infected and cancer patients (R. Contreras-Galindo et al.,...
10.
Stelzer A, Frank A, Kratz J, Swanson M, Gonzalez-Hernandez M, Lee J, et al.
Nat Chem Biol
. 2011 Jun;
7(8):553-9.
PMID: 21706033
Current approaches used to identify protein-binding small molecules are not suited for identifying small molecules that can bind emerging RNA drug targets. By docking small molecules onto an RNA dynamic...